4-(2′-Chlorobenzyloxy)-3,5-dimethylphenylboronic acid
4-(2′-Chlorobenzyloxy)-3,5-dimethylphenylboronic acid (CAS: 849052-15-9) is an organoboronic acid derivative with the molecular formula C15H16BClO3 and a molecular weight of 290.55 g/mol. This compound functions as a versatile building block in organic synthesis. It is particularly valuable in cross-coupling reactions, such as Suzuki-Miyaura coupling, for the formation of carbon-carbon bonds. Its structure makes it suitable for the introduction of a substituted phenyl group into complex molecules.
- Synonyms
- C15H16BClO3

Suzuki-Miyaura Coupling Reagent
This boronic acid is a key reactant in palladium-catalyzed Suzuki-Miyaura cross-coupling reactions, facilitating the synthesis of biaryl compounds and other complex organic structures.
Organic Synthesis Intermediate
It serves as a valuable intermediate in multi-step syntheses, enabling the introduction of the 4-(2′-chlorobenzyloxy)-3,5-dimethylphenyl moiety into target molecules.
Research and Development
Utilised in academic and industrial research laboratories for exploring new synthetic pathways and developing novel chemical entities.
| Molecular weight | 290.55 |
|---|---|
| Empirical formula | C15H16BClO3 |
| Melting point | 234-238 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(2′-Chlorobenzyloxy)-3,5-dimethylphenylboronic acid used for?
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4-(2′-Chlorobenzyloxy)-3,5-dimethylphenylboronic acid is primarily used as a building block in organic synthesis, especially in Suzuki-Miyaura cross-coupling reactions, and for research and development purposes.
What is the CAS number and chemical formula for 4-(2′-Chlorobenzyloxy)-3,5-dimethylphenylboronic acid?
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The CAS number is 849052-15-9 and the empirical formula is C15H16BClO3.
What grade and purity does Tech Serve Solutions supply for 4-(2′-Chlorobenzyloxy)-3,5-dimethylphenylboronic acid?
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Tech Serve Solutions supplies this product for research and development use. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product specifications. Please refer to the product specifications for available grades and purity.
How should 4-(2′-Chlorobenzyloxy)-3,5-dimethylphenylboronic acid be handled?
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Handle with appropriate personal protective equipment including a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust. Ensure adequate ventilation. The compound is classified as causing skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). It may also cause long lasting harmful effects to aquatic life (H413).
How is 4-(2′-Chlorobenzyloxy)-3,5-dimethylphenylboronic acid packed and exported?
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Tech Serve Solutions expertly packs and exports chemicals worldwide, ensuring compliance with all relevant shipping regulations and customs requirements for safe and secure international delivery.
How can I request a sample or quote for 4-(2′-Chlorobenzyloxy)-3,5-dimethylphenylboronic acid?
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You can request a sample or a quote by contacting our sales team directly through our website or by calling us. Please specify the product name and CAS number.
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