4′-(2-Chloroacetyl)acetanilide
4′-(2-Chloroacetyl)acetanilide (CAS 140-49-8) is an organic compound with the linear formula ClCH2COC6H4NHCOCH3 and a molecular weight of 211.64 g/mol. This acetanilide derivative serves as a valuable intermediate in organic synthesis, particularly in the preparation of more complex molecules. Its structure, featuring both a chloroacetyl group and an acetamido group, makes it a versatile building block for introducing specific functionalities in chemical research and development.
- IUPAC
- 4-(2-Chloroacetyl)acetanilide

Organic Synthesis Intermediate
Utilised as a key building block in the synthesis of various organic compounds. Its reactive chloroacetyl group allows for straightforward derivatisation.
Pharmaceutical Research
Employed in the development of novel pharmaceutical agents. The compound can be incorporated into molecular structures being investigated for therapeutic properties.
Chemical Research and Development
Serves as a reagent in academic and industrial R&D settings for exploring new chemical reactions and molecular architectures. It is useful for constructing molecules with specific functional groups.
| Molecular weight | 211.64 |
|---|---|
| Linear formula | ClCH2COC6H4NHCOCH3 |
| Assay | 97% |
| Melting point | 216-219 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4′-(2-Chloroacetyl)acetanilide primarily used for?
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4′-(2-Chloroacetyl)acetanilide is primarily used as a valuable intermediate and building block in organic synthesis and chemical research and development, including pharmaceutical research.
What are the CAS number and molecular formula for 4′-(2-Chloroacetyl)acetanilide?
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The CAS number is 140-49-8, and its linear formula is ClCH2COC6H4NHCOCH3.
What grade and purity does Tech Serve Solutions supply for 4′-(2-Chloroacetyl)acetanilide?
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Tech Serve Solutions supplies 4′-(2-Chloroacetyl)acetanilide with an assay of 97%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the primary safety and handling considerations for this compound?
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This compound is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment including a dust mask (type N95), eyeshields, and gloves should be used. Ensure good ventilation.
How is 4′-(2-Chloroacetyl)acetanilide packed and shipped?
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Tech Serve Solutions exports fine chemicals globally. Product packaging is designed to maintain integrity during transit, adhering to international shipping regulations for chemical substances.
How can I request a quote or sample for 4′-(2-Chloroacetyl)acetanilide?
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To request a quote or a sample, please contact our sales team through the website or by phone, providing the product name and CAS number (140-49-8).
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