(−)-3-(Trifluoroacetyl)camphor
(−)-3-(Trifluoroacetyl)camphor (CAS: 207742-84-5, Formula: C12H15F3O2) is a chiral fluorinated ketone with a molecular weight of 248.24 g/mol. It is primarily utilised as a chiral auxiliary and building block in asymmetric synthesis. Its unique trifluoroacetyl group and camphor backbone enable stereoselective transformations, making it valuable in the development of enantiomerically pure compounds for research and specialised chemical manufacturing.
- IUPAC
- 3-(Trifluoroacetyl)-L-camphor

Chiral Auxiliary in Asymmetric Synthesis
This compound serves as an effective chiral auxiliary, guiding stereoselective reactions to produce enantiomerically enriched products. Its structure facilitates high levels of diastereoselectivity in various synthetic transformations.
Building Block for Complex Molecules
As a chiral organic building block, it can be incorporated into the synthesis of complex molecules. It is particularly useful in the preparation of pharmaceuticals and agrochemicals where specific stereochemistry is critical.
Reagent in Organic Chemistry Research
It is employed in academic and industrial research laboratories for exploring new synthetic methodologies and developing novel chiral catalysts. Its well-defined stereochemical properties make it a reliable tool for fundamental studies.
| Molecular weight | 248.24 |
|---|---|
| Empirical formula | C12H15F3O2 |
| Assay | 98% |
| Density | 1.172 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.451(lit.) |
| Optical activity | [α]19/D −148.0°, c = 2.5 in methylene chloride |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 82 °C / 179.6 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (−)-3-(Trifluoroacetyl)camphor used for?
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It is primarily used as a chiral auxiliary and building block in asymmetric synthesis for creating enantiomerically pure compounds.
What are the CAS number and formula for (−)-3-(Trifluoroacetyl)camphor?
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The CAS number is 207742-84-5, and the empirical formula is C12H15F3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (−)-3-(Trifluoroacetyl)camphor with an assay of 98%. This product is not specified as USP, BP, or EP grade and is intended for research and technical applications.
How should (−)-3-(Trifluoroacetyl)camphor be handled?
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This compound is classified as a Warning. It can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Always use appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, and handle in a well-ventilated area.
How is this chemical packed and shipped?
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Packaging and shipping adhere to regulations for hazardous materials, including transport under NA 1993 / PGIII. Specific details for export are available upon request.
How can I request a sample or quote?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing the product name and CAS number (207742-84-5).
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