3-Methylpiperidine
3-Methylpiperidine (CAS: 626-56-2, C6H13N, MW: 99.17) is a valuable heterocyclic organic compound. Available from Tech Serve Solutions with an assay of 99%, this chemical serves as a key building block in various synthetic pathways. Its primary applications lie in the development of novel pharmaceutical agents and complex organic molecules, contributing to advancements in medicinal chemistry and materials science.
- IUPAC
- β-Pipecoline,3-Pipecoline
- Synonyms
- β-Pipecoline3-Pipecoline

Pharmaceutical Intermediate
3-Methylpiperidine is a critical reactant in the synthesis of various pharmacologically active compounds. It is utilised in the development of potential treatments for conditions such as hepatitis B, chronic pain via CB2 receptor agonism, and in the creation of selective serotonin 5-HT6 receptor antagonists.
Kinase Inhibitor Synthesis
This compound is employed in the synthesis of aurora kinase inhibitors. These inhibitors are of significant interest in oncology research due to their role in regulating cell division.
NPC1L1 Inhibitor Development
3-Methylpiperidine is a precursor in the synthesis of spiroimidazolidinone NPC1L1 inhibitors, which are explored for their potential in managing cholesterol absorption.
Heterocyclic Compound Synthesis
As a piperidine derivative, it is broadly applicable in the synthesis of diverse heterocyclic structures, including 1,3,5-Oxadiazinones, contributing to the field of organic synthesis.
| Molecular weight | 99.17 |
|---|---|
| Empirical formula | C6H13N |
| Assay | 99% |
| Boiling point | 125-126 °C/763 mmHg(lit.) |
| Density | 0.845 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.447(lit.) |
| Application | Reactant for synthesis of:• Phenylpropenamide derivatives for anti-hepatitis B virus activity1• CB2 receptor agonists for treatment of chronic pain2• Aurora kinase inhibitors3• Spiroimidazolidinone NPC1L1 inhibitors4• 1,3,5-Oxadiazinones5• Selective serotonin 5-HT6 receptor antagonists6 |


Hazard statements
- H225Highly flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 21 °C / 69.8 °F |
| Transport (UN / ADR) | UN 1993BF 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 16-23 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Methylpiperidine used for?
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3-Methylpiperidine is a reactant in the synthesis of various compounds, including phenylpropenamide derivatives for anti-hepatitis B virus activity, CB2 receptor agonists for chronic pain, aurora kinase inhibitors, spiroimidazolidinone NPC1L1 inhibitors, 1,3,5-Oxadiazinones, and selective serotonin 5-HT6 receptor antagonists.
What are the CAS number and formula for 3-Methylpiperidine?
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The CAS number is 626-56-2 and the empirical formula is C6H13N.
What grade and purity does Tech Serve Solutions supply for 3-Methylpiperidine?
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Tech Serve Solutions supplies 3-Methylpiperidine with an assay of 99%. We do not represent this product as USP, BP, EP or any other pharmacopoeia grade.
How should 3-Methylpiperidine be handled safely?
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3-Methylpiperidine is a highly flammable liquid and vapour (H225) and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area, keeping away from heat and ignition sources.
Is 3-Methylpiperidine a controlled substance?
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The provided data does not indicate that 3-Methylpiperidine is a controlled substance.
How is 3-Methylpiperidine packed, shipped, and exported?
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3-Methylpiperidine is shipped and exported in compliance with UN 1993 BF 3 / PGII regulations for flammable liquids. Packing is done according to international safety standards for hazardous materials.
How can I request a sample or quote for 3-Methylpiperidine?
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To request a sample or a quote for 3-Methylpiperidine, please contact our sales team via the website or email, providing your specific requirements.
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