3-Methylbutylzinc bromide solution
3-Methylbutylzinc bromide solution (CAS 92274-43-6), with the linear formula (CH3)2CHCH2CH2ZnBr and a molecular weight of 216.43 g/mol, is a vital organozinc reagent. Supplied as a 0.5 M solution in THF, it is primarily utilised in organic synthesis for carbon-carbon bond formation via coupling reactions and as a nucleophilic source of the 3-methylbutyl group. Its reactivity makes it indispensable in the development of complex molecules within research and industrial chemistry.

Organic Synthesis Reagent
Employed in organometallic chemistry for carbon-carbon bond formation, particularly in Negishi coupling reactions. It serves as a key building block for introducing the 3-methylbutyl moiety into organic frameworks.
Intermediate for Complex Molecules
Facilitates the synthesis of pharmaceutical intermediates and advanced materials. Its controlled reactivity allows for precise functionalization in multi-step synthetic routes.
Specialty Chemical Manufacturing
Used in the industrial production of fine chemicals requiring the incorporation of a branched alkyl chain. The solution's stability in THF aids in handling and reaction control.
| Molecular weight | 216.43 |
|---|---|
| Linear formula | (CH3)2CHCH2CH2ZnBr |
| Density | 0.97 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |



Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Methylbutylzinc bromide solution used for?
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3-Methylbutylzinc bromide solution is used in organic synthesis for carbon-carbon bond formation, acting as a nucleophilic reagent to introduce the 3-methylbutyl group into target molecules, and is particularly valuable in the synthesis of complex organic compounds and pharmaceutical intermediates.
What is the CAS number and formula for 3-Methylbutylzinc bromide solution?
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The CAS number is 92274-43-6 and the linear formula is (CH3)2CHCH2CH2ZnBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Methylbutylzinc bromide solution at a concentration of 0.5 M in THF. We do not claim USP, BP, or EP grade unless explicitly stated in the product specifications.
How should 3-Methylbutylzinc bromide solution be handled safely?
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This solution is highly flammable (H225) and may cause serious eye irritation (H319) and respiratory irritation (H335). It is also suspected of causing cancer (H351) and may form explosive peroxides. Handle with appropriate personal protective equipment (P210, P261, P281, P305 + P351 + P338) in a well-ventilated area, away from ignition sources. Store at 2-8°C.
Is 3-Methylbutylzinc bromide solution a controlled substance?
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The provided data does not indicate that 3-Methylbutylzinc bromide solution is a controlled substance.
How is 3-Methylbutylzinc bromide solution packed and shipped?
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3-Methylbutylzinc bromide solution is shipped under UN 2924, hazard class 8(3), packing group II, reflecting its corrosive and flammable nature. Packaging is designed to maintain stability and safety during transport.
How can I request a sample or quote for 3-Methylbutylzinc bromide solution?
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To request a sample or quote, please contact the Tech Serve Solutions sales team through our website or by phone, providing your specific requirements and shipping details.
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