3-Methyl-2-furoic acid
3-Methyl-2-furoic acid (CAS 4412-96-8, C6H6O3) is a heterocyclic organic compound with a molecular weight of 126.11 g/mol. This furan derivative serves as a valuable building block in chemical synthesis. It is primarily utilised in palladium-catalyzed cross-coupling reactions to create arylated heterocycles and in asymmetric hydrogenation processes, contributing to the development of complex organic molecules.
- IUPAC
- 3-Methylfuran-2-carboxylic acid
Palladium-Catalyzed Cross-Coupling Reactions
This compound is employed in palladium-catalyzed cross-coupling reactions between heteroaryl carboxylic acids and aryl bromides. This application facilitates the synthesis of arylated heterocyclic compounds, which are important in various fields of chemistry.
Asymmetric Hydrogenation
3-Methyl-2-furoic acid is also utilised as a component in palladium-catalyzed asymmetric hydrogenation reactions. This process is crucial for the stereoselective synthesis of chiral molecules.
Organic Synthesis Intermediate
As a furan derivative and heterocyclic building block, it finds general application as an intermediate in organic synthesis for constructing more complex molecular architectures.
| Molecular weight | 126.11 |
|---|---|
| Empirical formula | C6H6O3 |
| Assay | 97% |
| Application | Used in a palladium-catalyzed cross-coupling between heteroaryl carboxylic acids and aryl bromides leading to arylated heterocycles.1 Also used in a palladium-catalyzed asymmetric hydrogenation.2 |
| Melting point | 134-138 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Methyl-2-furoic acid used for?
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3-Methyl-2-furoic acid (CAS 4412-96-8) is used in palladium-catalyzed cross-coupling reactions to form arylated heterocycles and in palladium-catalyzed asymmetric hydrogenation.
What is the CAS number and molecular formula of 3-Methyl-2-furoic acid?
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The CAS number for 3-Methyl-2-furoic acid is 4412-96-8, and its molecular formula is C6H6O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Methyl-2-furoic acid with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for 3-Methyl-2-furoic acid?
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3-Methyl-2-furoic acid is classified as a Warning substance (GHS07) and causes skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Handle in a well-ventilated area and avoid dust formation. Store in a cool, dry place.
Is 3-Methyl-2-furoic acid a controlled substance?
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Based on the provided data, 3-Methyl-2-furoic acid is not indicated as a controlled substance.
How is 3-Methyl-2-furoic acid packaged, shipped, and exported?
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3-Methyl-2-furoic acid is packaged according to industry standards for fine chemicals. Tech Serve Solutions, as a global supplier and exporter, ensures compliant shipping and handling for international orders.
How can I request a sample or quote for 3-Methyl-2-furoic acid?
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To request a sample or a quotation for 3-Methyl-2-furoic acid, please contact our sales department through the website or via direct inquiry, providing your contact details and quantity requirements.
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