3-Methoxybenzenesulfonyl chloride
3-Methoxybenzenesulfonyl chloride (CAS: 10130-74-2; Formula: CH3OC6H4SO2Cl; Molar Mass: 206.65) is a versatile organic building block and sulfonyl halide. Characterised by its reactive sulfonyl chloride group and methoxy-substituted benzene ring, it is primarily employed in organic synthesis for the introduction of the 3-methoxybenzenesulfonyl moiety into various molecules. This compound serves as a crucial intermediate in the development of pharmaceuticals and other fine chemicals.
Organic Synthesis Intermediate
Utilised as a key reagent in organic synthesis for derivatisation and functional group transformations. Its sulfonyl chloride functionality readily reacts with nucleophiles like alcohols, amines, and thiols.
Pharmaceutical Precursor
Serves as a valuable building block in the synthesis of complex pharmaceutical compounds. The 3-methoxybenzenesulfonyl group can be incorporated into drug candidates to modulate their biological activity and pharmacokinetic properties.
Fine Chemical Manufacturing
Employed in the production of various fine chemicals and specialty materials. Its reactivity allows for its integration into diverse synthetic pathways requiring sulfonyl functionalities.
| Molecular weight | 206.65 |
|---|---|
| Linear formula | CH3OC6H4SO2Cl |
| Assay | 96% |
| Density | 1.460 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5560(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Methoxybenzenesulfonyl chloride used for?
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3-Methoxybenzenesulfonyl chloride (CAS: 10130-74-2) is primarily used as a building block in organic synthesis, particularly for introducing the 3-methoxybenzenesulfonyl group into other molecules for pharmaceutical and fine chemical applications.
What are the CAS number and chemical formula for 3-Methoxybenzenesulfonyl chloride?
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The CAS number is 10130-74-2 and the linear chemical formula is CH3OC6H4SO2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Methoxybenzenesulfonyl chloride with a minimum assay of 96%. This is a technical grade suitable for research and synthesis, and is not represented as USP, BP, or EP.
What are the primary safety hazards associated with 3-Methoxybenzenesulfonyl chloride?
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3-Methoxybenzenesulfonyl chloride is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including gloves, goggles, face shield, and suitable respiratory protection, is essential during handling. It is a corrosive material.
How is 3-Methoxybenzenesulfonyl chloride packed and shipped?
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3-Methoxybenzenesulfonyl chloride is shipped as UN 3265, Class 8, Packing Group II. TSS ensures all shipments comply with relevant dangerous goods regulations for safe export.
How can I request a sample or quote for 3-Methoxybenzenesulfonyl chloride?
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Please contact our sales team via the website or by calling us directly to request a sample or obtain a quotation for 3-Methoxybenzenesulfonyl chloride.
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