3-Hydroxypyridine N-oxide
3-Hydroxypyridine N-oxide (CAS 6602-28-4, C5H5NO2) is a key heterocyclic building block with a molecular weight of 111.10 g/mol. This pyridine derivative is primarily employed in chemical synthesis and research. Its applications include serving as a substrate in biochemical studies, particularly in understanding enzyme specificity, such as that of dimethyl sulfoxide reductase.
- IUPAC
- 3-Pyridinol N-oxide
- Synonyms
- 3-Pyridinol N-oxide

Biochemical Research
Utilised in studies investigating enzyme substrate specificity. For instance, it has been used to explore the function of dimethyl sulfoxide reductase isolated from Escherichia coli.
Chemical Synthesis
Serves as a valuable intermediate and building block in the synthesis of more complex organic molecules, particularly those containing pyridine ring systems.
Heterocyclic Chemistry
As a derivative of pyridine, it contributes to the field of heterocyclic chemistry, offering a functionalised N-oxide moiety for further reactions.
| Molecular weight | 111.10 |
|---|---|
| Empirical formula | C5H5NO2 |
| Assay | 99% |
| Application | 3-Hydroxypyridine N-oxide was used to study the substrate specificity of dimethyl sulfoxide reductase, isolated from anaerobically grown Escherichia coli1. |
| Melting point | 190-192 °C(lit.) |


Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38-40 |
| Safety statements (S) | 26-27-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Hydroxypyridine N-oxide used for?
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3-Hydroxypyridine N-oxide is used in biochemical research, particularly for studying enzyme substrate specificity (e.g., dimethyl sulfoxide reductase), and as a building block in chemical synthesis.
What is the CAS number and chemical formula for 3-Hydroxypyridine N-oxide?
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The CAS number is 6602-28-4, and the chemical formula is C5H5NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Hydroxypyridine N-oxide with a minimum assay of 99%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the primary safety concerns when handling 3-Hydroxypyridine N-oxide?
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3-Hydroxypyridine N-oxide is classified with a 'Warning' signal word and carries hazards including H302 (Harmful if swallowed), H312 (Harmful in contact with skin), H315 (Causes skin irritation), H319 (Causes serious eye irritation), H332 (Harmful if inhaled), H335 (May cause respiratory irritation), and H351 (Suspected of causing cancer). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used. Ensure adequate ventilation and avoid dust formation.
Is 3-Hydroxypyridine N-oxide a controlled substance?
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The provided data does not indicate that 3-Hydroxypyridine N-oxide is a controlled substance.
How can I request a sample or quote for 3-Hydroxypyridine N-oxide?
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To request a sample or quote, please use the contact form on our website or call our sales department, referencing product CAS 6602-28-4.
How is 3-Hydroxypyridine N-oxide packed and exported?
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3-Hydroxypyridine N-oxide is carefully packed to ensure safe transit and is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations.
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