3′-Deoxyguanosine
3′-Deoxyguanosine (CAS: 3608-58-0) is a guanosine analogue with the molecular formula C10H13N5O4 and a molecular weight of 267.24 g/mol. This biochemical compound serves as a ligand for enzyme and receptor studies, facilitating structural analysis. It is also utilised for its ability to selectively inhibit transcription while leaving polyadenylation unaffected. As a specialised nucleoside analog, it finds applications in molecular biology research.
Enzyme and Receptor Ligand
3′-Deoxyguanosine acts as a complexing ligand for enzymes, such as purine nucleoside phosphorylase (PNP), and receptors, including G-coupled receptors, to aid in structure determination and analysis.
Transcriptional Regulation
This compound can be employed to selectively inhibit the process of transcription, offering a tool for researchers to study gene expression mechanisms without impacting polyadenylation.
Molecular Biology Research
As a nucleoside analog, 3′-Deoxyguanosine is valuable in various molecular biology applications, including the study of nucleic acid metabolism and the development of biochemical assays.
| Molecular weight | 267.24 |
|---|---|
| Empirical formula | C10H13N5O4 |
| Application | 3′-Deoxyguanosine (3dG) is used as a complexing ligand for enzymes, such as purine nucleoside phosphorylase (PNP), and receptors, such as G-coupled receptors, to enable structure analysis. 3′-Deoxyguanosine may be used to selectively impair transcription but not polyadenylation. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3′-Deoxyguanosine used for?
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3′-Deoxyguanosine is used as a complexing ligand for enzymes and receptors to enable structure analysis and may be used to selectively impair transcription but not polyadenylation.
What is the CAS number and molecular formula for 3′-Deoxyguanosine?
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The CAS number for 3′-Deoxyguanosine is 3608-58-0 and its molecular formula is C10H13N5O4.
What grade and purity does Tech Serve Solutions supply for 3′-Deoxyguanosine?
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Tech Serve Solutions supplies 3′-Deoxyguanosine for research purposes. The specific assay and purity are detailed on the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade.
How should 3′-Deoxyguanosine be handled?
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Handle 3′-Deoxyguanosine with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Observe safety precautions suitable for chemical reagents and consult the safety data sheet for detailed guidance. The WGK Germany classification is 3, indicating a high hazard to water.
Is 3′-Deoxyguanosine available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 3′-Deoxyguanosine, and can ship to various international destinations.
How can I request a sample or quote for 3′-Deoxyguanosine?
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To request a sample or obtain a quote for 3′-Deoxyguanosine, please contact our sales department through the website or by phone. Specify the quantity required and your delivery location.
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