(3-Chloropropyl)trimethylsilane
(3-Chloropropyl)trimethylsilane (CAS: 2344-83-4) is an organosilicon compound with the molecular formula C6H15ClSi and a molecular weight of 150.72 g/mol. This halogenated hydrocarbon serves as a valuable building block in organic synthesis. It is utilised in the preparation of various chemical intermediates and compounds, demonstrating its utility in specialized chemical manufacturing processes and research.
Preparation of Quinolone Derivatives
(3-Chloropropyl)trimethylsilane has been employed in the synthesis of 8-(3-trimethylsilylpropoxy)quinolone, particularly under phase transfer catalytic conditions, highlighting its role in creating complex heterocyclic structures.
Synthesis of Silane-Functionalised Alcohols
The compound is instrumental in the preparation of 5-trimethylsilyl pentanol, a useful intermediate featuring both silyl and hydroxyl functional groups for further chemical modification.
Formation of Silylated Diamines
It is utilised in the synthesis of N-(tri-methylsilylalkyl)diamines, contributing to the development of organosilicon-based amine compounds.
| Molecular weight | 150.72 |
|---|---|
| Empirical formula | C6H15ClSi |
| Assay | ≥97.0% |
| Boiling point | 151 °C(lit.) |
| Density | 0.878 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.431 |
| Application | (3-Chloropropyl)trimethylsilane has been used in the preparation of:• 8-(3-trimethylsilylpropoxy)quinolone under phase transfer catalytic conditions1• 5-trimethylsilyl pentanol2• N-(tri-methylsilylalkyl)diamines3 |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 49 °C / 120.2 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (3-Chloropropyl)trimethylsilane used for?
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(3-Chloropropyl)trimethylsilane is used as a building block in organic synthesis, notably in the preparation of compounds such as 8-(3-trimethylsilylpropoxy)quinolone, 5-trimethylsilyl pentanol, and N-(tri-methylsilylalkyl)diamines.
What are the CAS number and formula for (3-Chloropropyl)trimethylsilane?
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The CAS number is 2344-83-4, and the molecular formula is C6H15ClSi.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (3-Chloropropyl)trimethylsilane with a purity of ≥97.0%. This is a technical/research grade material, and TSS does not represent it as USP, BP, or EP grade.
How should (3-Chloropropyl)trimethylsilane be handled safely?
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(3-Chloropropyl)trimethylsilane is a flammable liquid and vapour (H226) and can cause skin (H315), serious eye (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area.
Is (3-Chloropropyl)trimethylsilane a controlled substance?
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The provided data does not indicate that (3-Chloropropyl)trimethylsilane is a controlled substance.
How is (3-Chloropropyl)trimethylsilane packed and shipped?
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(3-Chloropropyl)trimethylsilane is classified under UN 1993, Class 3, Packing Group III. It is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations.
How can I request a sample or quote for (3-Chloropropyl)trimethylsilane?
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To request a sample or obtain a quote for (3-Chloropropyl)trimethylsilane, please contact our sales department through the website or by phone.
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