3-Chloroaniline
3-Chloroaniline (CAS 108-42-9), with the molecular formula ClC6H4NH2, is a halogenated aromatic amine. This compound serves as a critical building block in organic synthesis, primarily utilized in the production of dyes, pigments, and agricultural chemicals. Its specific structure lends itself to various coupling and derivatization reactions.
Dye and Pigment Intermediate
3-Chloroaniline is a key intermediate in the synthesis of azo dyes and pigments, contributing to a range of colours used in textiles and coatings. Its aromatic amine functionality allows for diazotization and subsequent coupling reactions.
Agrochemical Synthesis
This chemical is employed in the manufacturing of certain pesticides and herbicides. The chloro and amine groups on the benzene ring provide reactive sites for building more complex agrochemical molecules.
Pharmaceutical Building Block
In medicinal chemistry, 3-Chloroaniline can be used as a starting material or intermediate for synthesising active pharmaceutical ingredients (APIs). It provides a functionalised aromatic core for drug discovery programs.
Organic Synthesis Reagent
As a versatile organic building block, 3-Chloroaniline is valuable in general chemical synthesis for introducing the 3-chlorophenylamino moiety into various organic structures.
| Molecular weight | 127.57 |
|---|---|
| Linear formula | ClC6H4NH2 |
| Assay | 99% |
| Boiling point | 95-96 °C/11 mmHg(lit.) |
| Density | 1.206 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.594(lit.) |
| Vapour pressure | 1 mmHg (63.5 °C) |
| Melting point | −11-−9 °C(lit.) |
Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H331Toxic if inhaled
- H373May cause damage to organs through prolonged exposure
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P311Call a POISON CENTER or doctor
- P501Dispose of contents and container per local regulations
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 118 °C / 244.4 °F |
| Transport (UN / ADR) | UN 2019 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 23/24/25-33-50/53 |
| Safety statements (S) | 28-36/37-45-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Chloroaniline used for?
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3-Chloroaniline is primarily used as an intermediate in the synthesis of dyes, pigments, agrochemicals, and pharmaceuticals. It also serves as a general building block in organic synthesis.
What are the CAS number and formula for 3-Chloroaniline?
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The CAS number for 3-Chloroaniline is 108-42-9, and its molecular formula is ClC6H4NH2.
What grade and purity does Tech Serve Solutions supply for 3-Chloroaniline?
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Tech Serve Solutions supplies 3-Chloroaniline with an assay of 99%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 3-Chloroaniline be handled safely?
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3-Chloroaniline is a dangerous substance classified under GHS06, GHS08, and GHS09 symbols with the signal word 'Danger'. It is toxic if swallowed, in contact with skin, and if inhaled (H301-H311-H331), may cause damage to organs through prolonged or repeated exposure (H373), and is very toxic to aquatic life with long lasting effects (H410). Appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, must be used, and handling should occur in a well-ventilated area. Consult the Safety Data Sheet (SDS) for full details.
Is 3-Chloroaniline a controlled substance?
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The provided data does not indicate that 3-Chloroaniline is a controlled substance. However, users should always verify local regulations.
How is 3-Chloroaniline packed and shipped?
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3-Chloroaniline is shipped as a UN 2019 substance, classified under Hazard Class 6.1 (Toxic substances) with Packing Group II. TSS ensures compliance with all international shipping regulations for hazardous materials.
How can I request a quote or sample of 3-Chloroaniline?
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To request a quote or a sample of 3-Chloroaniline, please contact our sales team through the TSS website or via the provided contact details, specifying the product CAS number 108-42-9.
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