3-Chloro-2-methylbenzenesulfonyl chloride
3-Chloro-2-methylbenzenesulfonyl chloride (CAS: 80563-86-6) is an organic compound with the formula ClC6H3(CH3)SO2Cl and a molecular weight of 225.09 g/mol. This sulfonyl halide serves as a valuable building block in organic synthesis. It is employed in the preparation of various organic compounds, particularly those involving sulfonamide or sulfonate ester functionalities. Available from Tech Serve Solutions with an assay of 97%.

Organic Synthesis Intermediate
3-Chloro-2-methylbenzenesulfonyl chloride acts as a key intermediate in the synthesis of complex organic molecules. Its reactive sulfonyl chloride group readily participates in reactions to form sulfonamides and sulfonate esters.
Building Block for Pharmaceuticals
This compound can be utilised in the development pathways for pharmaceutical agents. The introduction of the 2-methylbenzenesulfonyl moiety can modulate the properties of potential drug candidates.
Reagent in Chemical Research
Researchers utilise 3-Chloro-2-methylbenzenesulfonyl chloride for its specific chemical reactivity in exploring new synthetic routes and developing novel chemical entities.
| Molecular weight | 225.09 |
|---|---|
| Linear formula | ClC6H3(CH3)SO2Cl |
| Assay | 97% |
| Melting point | 71-74 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Chloro-2-methylbenzenesulfonyl chloride used for?
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3-Chloro-2-methylbenzenesulfonyl chloride is primarily used as a building block in organic synthesis and as an intermediate in the preparation of pharmaceuticals and other complex organic molecules.
What is the CAS number and chemical formula for 3-Chloro-2-methylbenzenesulfonyl chloride?
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The CAS number is 80563-86-6 and the chemical formula is ClC6H3(CH3)SO2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Chloro-2-methylbenzenesulfonyl chloride with a minimum purity of 97%. This product is not intended for pharmaceutical, food, or any other regulated application unless explicitly stated otherwise in the product documentation.
How should 3-Chloro-2-methylbenzenesulfonyl chloride be handled?
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Handling requires significant precautions due to its corrosive nature. Protective equipment including eyeshields, face shields, gloves, and appropriate respiratory protection (e.g., N100 or P3 filters) is essential. It causes severe skin burns and eye damage (H314).
How is 3-Chloro-2-methylbenzenesulfonyl chloride shipped and exported?
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As a dangerous good (UN 3261, Class 8, Packing Group II), it is shipped and exported according to strict international regulations for hazardous materials.
How can I request a quote or sample of 3-Chloro-2-methylbenzenesulfonyl chloride?
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To request a quote or a sample, please contact the Tech Serve Solutions sales team via our website or direct contact details, specifying the product CAS number 80563-86-6.
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