3-Chloro-2-fluorophenylboronic acid
3-Chloro-2-fluorophenylboronic acid (CAS: 352535-82-1), with the molecular formula ClC6H3(F)B(OH)2 and a molecular weight of 174.37 g/mol, is an organoboron compound. This aryl boronic acid derivative is a valuable building block in organic synthesis, particularly in cross-coupling reactions. It is essential for constructing complex molecules in research and development settings.
- IUPAC
- 2-Fluoro-3-chlorophenylboronic acid,3-Chloro-2-fluorobenzeneboronic acid
- Synonyms
- 2-Fluoro-3-chlorophenylboronic acid3-Chloro-2-fluorobenzeneboronic acid
Suzuki-Miyaura Cross-Coupling
Utilised as a key reagent in Suzuki-Miyaura coupling reactions to form carbon-carbon bonds. This allows for the synthesis of biaryl compounds and other complex organic structures.
Pharmaceutical Intermediate Synthesis
Serves as a crucial intermediate in the development of novel pharmaceutical agents. Its structure allows for precise modification in drug discovery pipelines.
Organic Synthesis Building Block
A versatile building block in general organic synthesis, enabling the introduction of the 3-chloro-2-fluorophenyl moiety into target molecules.
Materials Science Research
Applicable in materials science for the synthesis of functional organic materials with specific electronic or optical properties.
| Molecular weight | 174.37 |
|---|---|
| Linear formula | ClC6H3(F)B(OH)2 |
| Melting point | 223 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Chloro-2-fluorophenylboronic acid used for?
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3-Chloro-2-fluorophenylboronic acid is primarily used as a building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions for the creation of carbon-carbon bonds. It also finds application as an intermediate in pharmaceutical research and materials science.
What is the CAS number and chemical formula for 3-Chloro-2-fluorophenylboronic acid?
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The CAS number is 352535-82-1, and the chemical formula is ClC6H3(F)B(OH)2.
What grade and purity does Tech Serve Solutions supply for 3-Chloro-2-fluorophenylboronic acid?
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Tech Serve Solutions supplies 3-Chloro-2-fluorophenylboronic acid as a research chemical. The specific assay and purity are detailed in the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade.
How should 3-Chloro-2-fluorophenylboronic acid be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the Safety Data Sheet (SDS) for comprehensive safety and handling information. This compound has a WGK Germany rating of 3.
Is 3-Chloro-2-fluorophenylboronic acid a controlled substance?
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The provided data does not indicate that 3-Chloro-2-fluorophenylboronic acid is a controlled substance.
How is 3-Chloro-2-fluorophenylboronic acid packed and shipped?
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Tech Serve Solutions, as a global supplier and exporter, ensures that 3-Chloro-2-fluorophenylboronic acid is packed and shipped in compliance with all relevant regulations for chemical substances, including international shipping standards.
How can I request a quote or sample for 3-Chloro-2-fluorophenylboronic acid?
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To request a quote or sample of 3-Chloro-2-fluorophenylboronic acid, please contact our sales department via the website or listed contact details, providing your specific requirements.
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