3-Chloro-2,2-dimethylpropionyl chloride
3-Chloro-2,2-dimethylpropionyl chloride (CAS: 4300-97-4) is an organic compound with the molecular formula ClCH2C(CH3)2COCl and a molecular weight of 154.01 g/mol. As an acid halide and a key building block, it is primarily utilised in chemical synthesis. Its reactive nature makes it valuable for introducing the 3-chloro-2,2-dimethylpropionyl group into various organic molecules, facilitating the creation of more complex structures.
- IUPAC
- β-Chloropivaloyl chloride,3-Chloropivaloyl chloride
- Synonyms
- ClCH2C(CH3)2COClβ-Chloropivaloyl chloride3-Chloropivaloyl chloride
Organic Synthesis Intermediate
This compound serves as a versatile intermediate in the synthesis of various organic molecules. Its acyl chloride functionality readily reacts with nucleophiles, enabling its use in esterification, amidation, and Friedel-Crafts acylation reactions.
Research and Development
3-Chloro-2,2-dimethylpropionyl chloride is employed in research laboratories for the development of new chemical entities and materials. Its specific structure allows for the introduction of a sterically hindered, halogenated acyl group.
Building Block for Complex Molecules
As a functionalised building block, it facilitates the construction of complex molecular architectures. The presence of both a reactive acyl chloride and a chlorine atom offers multiple reaction pathways for further derivatisation.
| Molecular weight | 154.01 |
|---|---|
| Linear formula | ClCH2C(CH3)2COCl |
| Assay | 98% |
| Boiling point | 85-86 °C/60 mmHg(lit.) |
| Density | 1.199 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.453(lit.) |
| Application | 3-Chloro-2,2-dimethylpropionyl chloride may be used in chemical synthesis studies. |
Hazard statements
- H314Causes severe skin burns and eye damage
- H330Fatal if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 63 °C / 145.4 °F |
| Transport (UN / ADR) | UN 3390 6.1/PG 1 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 26-34 |
| Safety statements (S) | 26-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Chloro-2,2-dimethylpropionyl chloride used for?
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3-Chloro-2,2-dimethylpropionyl chloride is used as a chemical intermediate and building block in organic synthesis and research and development.
What is the CAS number and chemical formula for 3-Chloro-2,2-dimethylpropionyl chloride?
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The CAS number is 4300-97-4 and the linear formula is ClCH2C(CH3)2COCl.
What grade and purity does Tech Serve Solutions supply for 3-Chloro-2,2-dimethylpropionyl chloride?
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Tech Serve Solutions supplies 3-Chloro-2,2-dimethylpropionyl chloride with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 3-Chloro-2,2-dimethylpropionyl chloride be handled?
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This compound is dangerous and causes severe skin burns and eye damage (H314), is fatal if inhaled (H330), and may cause respiratory irritation (H335). Handling requires appropriate personal protective equipment, including full-face respirators, gloves, goggles, and chemical-resistant clothing. Always consult the Safety Data Sheet before use.
How is 3-Chloro-2,2-dimethylpropionyl chloride packed and exported?
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3-Chloro-2,2-dimethylpropionyl chloride is available for purchase and export globally through Tech Serve Solutions. Specific packaging details will be provided upon request, adhering to international shipping regulations for hazardous materials.
How can I request a quote or sample for 3-Chloro-2,2-dimethylpropionyl chloride?
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To request a quote or a sample of 3-Chloro-2,2-dimethylpropionyl chloride, please contact the Tech Serve Solutions sales team via our website or direct inquiry channels.
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