3-Carboxy-5-nitrophenylboronic acid
3-Carboxy-5-nitrophenylboronic acid (CAS: 101084-81-5, C7H6BNO6) is a vital aryl boronic acid derivative supplied by Tech Serve Solutions. With a molecular weight of 210.94 g/mol, this compound serves as a key reactant in various synthetic processes, including copper-catalyzed chlorination and solid-phase synthesis. It is also instrumental in surface modification, such as immobilizing enzymes on silica for biochemical applications.
- IUPAC
- (3-Carboxy-5-nitrophenyl)boronic acid,3-(Dihydroxyboryl)-5-nitrobenzoic acid,3-Borono-5-nitrobenzoic acid,3-Carboxy-5-nitrobenzeneboronic acid,5-Carboxy-3-nitrobenzeneboronic acid
- Synonyms
- (3-Carboxy-5-nitrophenyl)boronic acid3-(Dihydroxyboryl)-5-nitrobenzoic acid3-Borono-5-nitrobenzoic acid3-Carboxy-5-nitrobenzeneboronic acid5-Carboxy-3-nitrobenzeneboronic acid
Copper-Catalyzed Chlorination
3-Carboxy-5-nitrophenylboronic acid is utilised as a reactant in copper-catalyzed chlorination reactions, enabling specific synthetic transformations in organic chemistry.
Solid-Phase Synthesis
This compound is employed in parallel solid-phase synthesis for the creation of complex molecules, such as azabicyclooctylidenemethylbenzamides with potential opioid agonist activity.
Enzyme Immobilization
It serves a crucial role in the immobilization of enzymes, like glucose oxidase and acetylcholinesterase, onto boronic acid-activated silica surfaces for biosensor development and research.
| Molecular weight | 210.94 |
|---|---|
| Empirical formula | C7H6BNO6 |
| Application | Reactant for:• Copper-catalyzed chlorination • Parallel solid-phase synthesis of azabicyclooctylidenemethylbenzamides as μ- and d-opioid agonistsUsed for:• Immobilization of glucose oxidase and acetylcholinesterase on boronic acid-activated silica surfaces |
| Melting point | 248-252 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Carboxy-5-nitrophenylboronic acid used for?
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3-Carboxy-5-nitrophenylboronic acid is used as a reactant in copper-catalyzed chlorination and in parallel solid-phase synthesis. It is also employed for the immobilization of enzymes on boronic acid-activated silica surfaces.
What is the CAS number and chemical formula for 3-Carboxy-5-nitrophenylboronic acid?
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The CAS number is 101084-81-5 and the empirical formula is C7H6BNO6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a research or technical grade chemical. We do not represent it as USP, BP, or EP grade unless explicitly stated in the product documentation. Please refer to the specific product Certificate of Analysis for detailed purity information.
How should 3-Carboxy-5-nitrophenylboronic acid be handled?
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This compound is classified as a Warning under GHS, with hazards including skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area. Avoid inhalation, ingestion, and contact with skin and eyes. Always consult the Safety Data Sheet (SDS) before use.
Is 3-Carboxy-5-nitrophenylboronic acid a controlled substance?
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Based on the provided data, 3-Carboxy-5-nitrophenylboronic acid is not indicated as a controlled substance.
How can I request a quote or sample?
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To request a quote or a sample of 3-Carboxy-5-nitrophenylboronic acid, please contact our sales team through the TSS website or by calling our customer service line.
How is 3-Carboxy-5-nitrophenylboronic acid packed and shipped?
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3-Carboxy-5-nitrophenylboronic acid is carefully packed according to international shipping regulations for chemical reagents. We export globally, ensuring compliance with all necessary documentation and safety standards for transportation.
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