3-Butoxypropylamine
3-Butoxypropylamine (CAS: 16499-88-0) is an organic compound with the linear formula CH3(CH2)3O(CH2)3NH2 and a molecular weight of 131.22 g/mol. This primary amine features a terminal butoxypropyl group, rendering it soluble in many organic solvents. It serves as a versatile building block in organic synthesis, particularly in the preparation of specialised ligands and complex molecules for chemical research and development.

Synthesis of Functionalised Ligands
3-Butoxypropylamine is employed in the synthesis of N-functionalised bis(phosphino)amine ligands. These ligands can incorporate ether, thioether, and pyridyl tethers, enabling diverse coordination chemistries for catalysis and materials science.
Organic Building Block
As a bifunctional molecule with amine and ether functionalities, it acts as a valuable intermediate in the construction of more complex organic structures. Its structure lends itself to modifications for specific synthetic targets in pharmaceutical and fine chemical research.
Chemical Synthesis Intermediate
This compound can be utilised in various organic transformations, including nucleophilic substitutions and derivatisations. Its predictable reactivity makes it a reliable component in multi-step synthetic pathways.
| Molecular weight | 131.22 |
|---|---|
| Linear formula | CH3(CH2)3O(CH2)3NH2 |
| Assay | 99% |
| Boiling point | 169-170 °C/756 mmHg(lit.) |
| Density | 0.853 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.426(lit.) |
| Application | 3-Butoxypropylamine may be used in the synthesis of N-functionalized bis(phosphino)amine ligands with ether, thioether and pyridyl tethers1. |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 63 °C / 145.4 °F |
| Transport (UN / ADR) | UN 2735PSN1 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Butoxypropylamine used for?
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3-Butoxypropylamine is primarily used as a building block in organic synthesis, particularly for preparing N-functionalised bis(phosphino)amine ligands with ether, thioether, and pyridyl tethers, and as an intermediate in chemical research and development.
What are the CAS number and formula for 3-Butoxypropylamine?
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The CAS number for 3-Butoxypropylamine is 16499-88-0, and its linear formula is CH3(CH2)3O(CH2)3NH2.
What grade and purity does Tech Serve Solutions supply for 3-Butoxypropylamine?
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Tech Serve Solutions supplies 3-Butoxypropylamine with a minimum purity of 99%. This product is suitable for laboratory and research purposes; TSS does not represent it as USP, BP, or EP grade.
How should 3-Butoxypropylamine be handled safely?
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3-Butoxypropylamine is corrosive and can cause severe skin burns and eye damage (H314). Appropriate personal protective equipment, including face shields, gloves, and chemical goggles, is essential. Handle only in well-ventilated areas or with appropriate respiratory protection. In case of contact, rinse cautiously with water for several minutes and seek immediate medical attention.
How is 3-Butoxypropylamine packed and shipped?
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3-Butoxypropylamine is classified under UN 2735, class 8, packing group II, indicating it is a corrosive material. It is packed and exported by Tech Serve Solutions in compliance with international transportation regulations for hazardous chemicals.
How can I request a quote or sample for 3-Butoxypropylamine?
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To request a quote or sample of 3-Butoxypropylamine, please contact the Tech Serve Solutions sales team via our website or directly by phone. Please specify the quantity required for your quotation or sample request.
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