3-Bromothiophene
3-Bromothiophene (CAS: 872-31-1, C4H3BrS, MW: 163.04) is a halogenated heterocyclic organic compound. This thiophene derivative is a valuable building block in organic synthesis, particularly for the construction of more complex molecules. Its reactivity makes it a useful intermediate in the development of pharmaceuticals, agrochemicals, and materials science applications. Tech Serve Solutions supplies 3-Bromothiophene for research and industrial chemical processes.
- IUPAC
- 3-Thienyl bromide
- Synonyms
- 3-Thienyl bromide
Organic Synthesis Intermediate
3-Bromothiophene serves as a key intermediate in various organic transformations. It is frequently employed in cross-coupling reactions, such as Suzuki or Stille couplings, to introduce the thiophene moiety into larger molecular structures. This is crucial for building complex organic frameworks found in active pharmaceutical ingredients and advanced materials.
Pharmaceutical Research and Development
The thiophene ring system is a common structural motif in many pharmaceuticals. 3-Bromothiophene is utilised as a versatile starting material or intermediate in the synthesis of novel drug candidates. Its incorporation can influence the pharmacokinetic and pharmacodynamic properties of potential therapeutics.
Materials Science
In materials science, thiophene derivatives are important components in the development of organic electronic materials, including conductive polymers and organic semiconductors. 3-Bromothiophene can be used to synthesise monomers for polymerisation or as a building block for functional organic molecules with tailored electronic properties.
| Molecular weight | 163.04 |
|---|---|
| Empirical formula | C4H3BrS |
| Assay | 97% |
| Grade | technical |
| Boiling point | 150 °C(lit.) |
| Density | 1.74 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.591(lit.) |
Hazard statements
- H226Flammable liquid and vapour
- H301Toxic if swallowed
- H310Fatal in contact with skin
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H330Fatal if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P301IF SWALLOWED
- P302IF ON SKIN
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 52 °C / 125.6 °F |
| Transport (UN / ADR) | UN 1993 3/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 10-23/24/25-36/37-43-51/53 |
| Safety statements (S) | 26-36/37-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Bromothiophene used for?
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3-Bromothiophene is primarily used as an intermediate in organic synthesis, for the development of pharmaceuticals, agrochemicals, and in materials science for creating organic electronic materials.
What are the CAS number and formula for 3-Bromothiophene?
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The CAS number for 3-Bromothiophene is 872-31-1, and its empirical formula is C4H3BrS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Bromothiophene with a technical grade and an assay of 97%.
How should 3-Bromothiophene be handled safely?
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3-Bromothiophene is a flammable liquid and vapour, and is toxic if swallowed, in contact with skin, or if inhaled. It can cause skin irritation, serious eye irritation, and respiratory irritation. Always handle with appropriate personal protective equipment, including safety shields, gloves, and respiratory protection, in a well-ventilated area. Refer to the Safety Data Sheet for detailed handling instructions.
Is 3-Bromothiophene a controlled substance?
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The provided data does not indicate that 3-Bromothiophene is a controlled substance.
How is 3-Bromothiophene packed and shipped?
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Tech Serve Solutions exports fine chemicals globally, adhering to all necessary regulations for safe transportation and handling of hazardous materials.
How can I request a quote or sample of 3-Bromothiophene?
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Please contact our sales team directly through our website or by phone to request a quote or a sample of 3-Bromothiophene.
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