3-Bromopyridine
3-Bromopyridine (CAS 626-55-1, C5H4BrN, MW 158.00) is a halogenated heterocyclic compound supplied by Tech Serve Solutions. This building block is characterised by its pyridine ring substituted with a bromine atom, making it a versatile reagent in organic synthesis. It finds utility in the preparation of complex molecules, particularly in pharmaceutical and agrochemical research, serving as a key intermediate for various biologically active compounds.
Nicotine Analog Synthesis
3-Bromopyridine has been employed in the synthesis of compounds such as <i>cis</i>-1-methyl-1,2,3,3<i>a</i>,4,8<i>b</i>-hexahydropyrrolo[3,2-<i>f]</i>pyrindine, a notable nicotine analog.
Boronic Acid Preparation
This compound serves as a precursor in the preparation of 3-pyridylboronic acid, a valuable reagent in Suzuki coupling reactions and other cross-coupling methodologies.
Heterocyclic Chemistry
As a halogenated heterocycle, 3-Bromopyridine is a fundamental building block in the construction of more complex heterocyclic systems relevant to medicinal chemistry.
| Molecular weight | 158.00 |
|---|---|
| Empirical formula | C5H4BrN |
| Assay | 99% |
| Grade | purum |
| Boiling point | 173 °C(lit.) |
| Density | 1.64 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.571(lit.) |
| Application | 3-Bromopyridine was used in the synthesis of cis-1-methyl-1,2,3,3a,4,8b-hexahydropyrrolo[3,2-f]pyrindine (a nicotine analog)1. It was also used in the preparation of 3-pyridylboronic acid2. |
Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 52 °C / 125.6 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 10-22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Bromopyridine used for?
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3-Bromopyridine is used as a building block in organic synthesis, notably in the preparation of nicotine analogs and pyridylboronic acids.
What are the CAS number and formula for 3-Bromopyridine?
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The CAS number for 3-Bromopyridine is 626-55-1, and its empirical formula is C5H4BrN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Bromopyridine with a purity of 99% (purum grade). This product is intended for laboratory and research use and is not represented as USP, BP, or EP grade.
What are the key safety considerations when handling 3-Bromopyridine?
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3-Bromopyridine is a flammable liquid and vapour (H226), is harmful if swallowed (H302), and causes skin (H315), eye (H319), and respiratory tract irritation (H335). Always handle with appropriate personal protective equipment, including safety glasses, gloves, and use in a well-ventilated area.
Is 3-Bromopyridine a controlled substance?
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The provided data does not indicate that 3-Bromopyridine is a controlled substance.
How is 3-Bromopyridine packed, shipped, and exported?
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3-Bromopyridine is typically packed in compliance with relevant transport regulations for flammable liquids. Tech Serve Solutions can export this chemical globally.
How can I request a quote or sample for 3-Bromopyridine?
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Please contact our sales department via the website or by phone to request a quotation or a sample of 3-Bromopyridine.
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