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3-(Bromomethyl)phenylboronic acid

CAS 51323-43-4BrCH2(C6H4)B(OH)2Chemical Synthesis

3-(Bromomethyl)phenylboronic acid (CAS: 51323-43-4) is an organoboron compound with the linear formula BrCH2(C6H4)B(OH)2 and a molecular weight of 214.85 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions. Its structure incorporates both a reactive bromomethyl group and a boronic acid moiety, enabling diverse chemical transformations for creating complex molecules. Supplied with an assay of 90%, it is suitable for research and development applications.

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3-(Bromomethyl)phenylboronic acid (BrCH2(C6H4)B(OH)2) — chemical structure, CAS 51323-43-4; Chemistry, fine chemical supplied by Tech Serve Solutions
Aryl Boronic AcidsBoronic AcidsChemical Synthesis
01 /Applications

Organic Synthesis Intermediate

Utilised as a versatile intermediate in the synthesis of complex organic molecules. The presence of both a bromomethyl group and a boronic acid function allows for sequential or diverse coupling reactions.

Cross-Coupling Reactions

Key reagent in palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura coupling. Enables the formation of new carbon-carbon bonds, crucial in medicinal chemistry and materials science.

Pharmaceutical Intermediate

Serves as a building block in the synthesis of potential pharmaceutical agents and drug discovery programmes. Facilitates the introduction of specific aryl or benzyl fragments into target compounds.

Materials Science

Employed in the development of novel organic materials, including polymers and functionalised surfaces, where its specific structural features can impart desired properties.

02 /Properties
Molecular weight214.85
Linear formulaBrCH2(C6H4)B(OH)2
Assay90%
Storage temperature2-8°C
Melting point224-228 °C
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
51323-43-4
MDL number
MFCD01632207
PubChem substance
24885494
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3-(Bromomethyl)phenylboronic acid used for?

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3-(Bromomethyl)phenylboronic acid is primarily used as a versatile intermediate in organic synthesis, particularly for cross-coupling reactions like Suzuki-Miyaura coupling, and in the development of pharmaceuticals and novel organic materials.

What are the CAS number and chemical formula for 3-(Bromomethyl)phenylboronic acid?

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The CAS number is 51323-43-4 and the linear formula is BrCH2(C6H4)B(OH)2.

What grade and purity does Tech Serve Solutions supply for 3-(Bromomethyl)phenylboronic acid?

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Tech Serve Solutions supplies 3-(Bromomethyl)phenylboronic acid with an assay of 90%. This product is intended for research and technical use; TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.

How should 3-(Bromomethyl)phenylboronic acid be handled and stored?

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Handle with appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves, in a well-ventilated area. Store at 2-8°C. It is classified as an irritant (H315, H319, H335).

Is 3-(Bromomethyl)phenylboronic acid a controlled substance?

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The provided data does not indicate that 3-(Bromomethyl)phenylboronic acid is a controlled substance.

How is 3-(Bromomethyl)phenylboronic acid typically packed and exported?

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This chemical is typically packed securely for safe transport and exported according to international shipping regulations for chemical substances.

How can I request a quote or sample for 3-(Bromomethyl)phenylboronic acid?

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To request a quote or sample, please contact our sales team through the website or by calling our dedicated line, providing the product name and CAS number.

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