3-Bromoaniline
3-Bromoaniline (CAS: 591-19-5; Formula: BrC6H4NH2; MW: 172.02) is a key organic intermediate and building block. This aromatic amine, characterised by a bromine substituent on the aniline ring, is widely used in chemical synthesis. It serves as a crucial precursor in the development of diverse chemical entities, including pharmaceutical intermediates and speciality chemicals, leveraging its reactive amine and aryl bromide functionalities for further molecular elaboration.
- Synonyms
- 3-Aminobromobenzenemeta-Bromoanilinem-Bromoaniline
Synthesis of Heterocyclic Compounds
3-Bromoaniline is employed as a starting material in the construction of various heterocyclic ring systems. Its structure allows for cyclization reactions leading to complex molecules, often found in medicinal chemistry research and materials science.
Pharmaceutical Intermediate Development
This compound acts as a valuable building block for synthesizing active pharmaceutical ingredients (APIs) and related intermediates. The presence of both an amino group and a bromine atom facilitates diverse synthetic transformations.
Organic Synthesis and Research
As a versatile reagent, 3-Bromoaniline is integral to numerous organic synthesis pathways. It is utilized in research laboratories for developing novel compounds and exploring new chemical reactions.
Precursor for Aminoquinazolines
3-Bromoaniline has been documented for use in the synthesis of amino-substituted quinazolines, a class of compounds with significant biological activity and potential therapeutic applications.
| Molecular weight | 172.02 |
|---|---|
| Linear formula | BrC6H4NH2 |
| Assay | 98% |
| Boiling point | 251 °C(lit.) |
| Density | 1.58 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.625(lit.) |
| Application | 3-Bromoaniline was used in the synthesis of amino substituted quinazoline1. |
| Melting point | 15-18 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 21/22-36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Bromoaniline used for?
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3-Bromoaniline is primarily used as a building block in organic synthesis, including the development of pharmaceutical intermediates and heterocyclic compounds like aminoquinazolines.
What are the CAS number and formula for 3-Bromoaniline?
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The CAS number for 3-Bromoaniline is 591-19-5, and its linear formula is BrC6H4NH2.
What grade and purity does Tech Serve Solutions supply for 3-Bromoaniline?
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Tech Serve Solutions supplies 3-Bromoaniline with an assay of 98%. This product is suitable for research and technical applications; we do not represent it as USP, BP, or EP grade.
How should 3-Bromoaniline be handled safely?
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3-Bromoaniline is harmful if swallowed, inhaled, or in contact with skin, and causes skin and eye irritation, as well as respiratory irritation. Handle with appropriate personal protective equipment, including gloves, eyeshields, and respiratory protection, in a well-ventilated area.
Is 3-Bromoaniline a controlled substance?
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The provided data does not indicate that 3-Bromoaniline is a controlled substance. However, users should always verify local regulations.
How is 3-Bromoaniline packed and exported?
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3-Bromoaniline is exported according to international shipping regulations for hazardous materials, typically UN 2810, Class 6.1, Packing Group III. Packaging is designed to ensure safety and integrity during transit.
How can I request a quote or sample for 3-Bromoaniline?
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To request a quote or sample of 3-Bromoaniline, please contact our sales team through the TSS website or by calling our dedicated customer service line.
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