3-Bromo-5-methoxyphenylboronic acid
3-Bromo-5-methoxyphenylboronic acid (CAS: 849062-12-0) is a valuable aryl boronic acid derivative with the molecular formula C7H8BBrO3 and a molecular weight of 230.85. This crystalline compound serves as a key reactant in advanced organic synthesis, particularly in the preparation of complex molecules. Its utility is noted in the synthesis of pyrazolopyrimidinamine derivatives, which are investigated for their potential as kinase inhibitors.
Synthesis of Kinase Inhibitors
Serves as a crucial building block in the preparation of pyrazolopyrimidinamine derivatives. These compounds are explored for their inhibitory activity against tyrosine and phosphoinositide kinases, relevant targets in medicinal chemistry research.
Organometallic Reagent in Organic Synthesis
As an aryl boronic acid, this compound is a versatile reagent in cross-coupling reactions. It facilitates the formation of carbon-carbon bonds, enabling the construction of complex molecular architectures.
Intermediate for Pharmaceutical Research
Utilised in the development of novel pharmaceutical candidates. Its specific substitution pattern makes it valuable for introducing tailored functionalities into potential drug molecules.
| Molecular weight | 230.85 |
|---|---|
| Empirical formula | C7H8BBrO3 |
| Assay | ≥95% |
| Form | crystalline |
| Application | Reactant for:• Preparation of pyrazolopyrimidinamine derivatives as tyrosine and phosphinositide kinase inhibitors1 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Bromo-5-methoxyphenylboronic acid used for?
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3-Bromo-5-methoxyphenylboronic acid is used as a reactant in organic synthesis, notably for preparing pyrazolopyrimidinamine derivatives investigated as kinase inhibitors.
What are the CAS number and formula for 3-Bromo-5-methoxyphenylboronic acid?
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The CAS number is 849062-12-0, and the empirical formula in Hill notation is C7H8BBrO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Bromo-5-methoxyphenylboronic acid with an assay of ≥95%. This is a research-grade chemical and not intended for USP, BP, EP, or pharmaceutical use.
How should 3-Bromo-5-methoxyphenylboronic acid be handled?
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Handle with appropriate personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. This compound is classified under WGK 2 in Germany, indicating it is hazardous to water.
Can Tech Serve Solutions export this chemical?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 3-Bromo-5-methoxyphenylboronic acid.
How can I request a sample or quote for 3-Bromo-5-methoxyphenylboronic acid?
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Please contact our sales department via the website or your dedicated account manager to request a sample or a formal quotation.
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