3-Bromo-2,6-difluorophenylboronic acid
3-Bromo-2,6-difluorophenylboronic acid (CAS 352535-84-3), with the linear formula BrC6H2(F2)B(OH)2 and a molecular weight of 236.81 g/mol, is a key organometallic reagent. This trisubstituted aryl boronic acid serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions. It is widely employed in the development of complex molecules for pharmaceutical research and materials science, offering a difluorinated and brominated phenylboronic acid scaffold.
- Synonyms
- 3-Bromo-2,6-difluorobenzeneboronic acid
Organic Synthesis Intermediate
Utilised as a versatile building block in Suzuki-Miyaura cross-coupling reactions to introduce the 3-bromo-2,6-difluorophenyl moiety into target molecules. This is crucial for constructing complex organic frameworks.
Pharmaceutical Research
A significant intermediate in the synthesis of potential drug candidates. Its unique substitution pattern can impart specific electronic and steric properties to biologically active compounds.
Materials Science
Employed in the development of novel organic materials, such as polymers and liquid crystals, where precise functionalisation is required for tailored properties.
| Molecular weight | 236.81 |
|---|---|
| Linear formula | BrC6H2(F2)B(OH)2 |
| Melting point | 122-127 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Bromo-2,6-difluorophenylboronic acid used for?
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3-Bromo-2,6-difluorophenylboronic acid is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions, and in pharmaceutical research and materials science.
What are the CAS number and formula for 3-Bromo-2,6-difluorophenylboronic acid?
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The CAS number is 352535-84-3 and the linear formula is BrC6H2(F2)B(OH)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Bromo-2,6-difluorophenylboronic acid with a purity of 97%+. This is a research-grade chemical and is not represented as USP, BP, or EP.
What are the safety precautions for handling 3-Bromo-2,6-difluorophenylboronic acid?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the Safety Data Sheet for full details.
How is 3-Bromo-2,6-difluorophenylboronic acid packed and shipped?
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This compound is carefully packed and exported by Tech Serve Solutions in compliance with international shipping regulations for chemicals.
How can I request a sample or quote for 3-Bromo-2,6-difluorophenylboronic acid?
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To request a sample or a quotation, please contact our sales department via the website or by calling our main office.
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