(±)-3-(Boc-aminomethyl)piperidine
(±)-3-(Boc-aminomethyl)piperidine (CAS 142643-29-6) is a protected piperidine derivative with the molecular formula C11H22N2O2 and a molecular weight of 214.30 g/mol. It serves as a valuable building block in organic synthesis, particularly for the preparation of complex molecules. Its applications include use as a reagent in the synthesis of Tylophorine analogs and in enzymatic acylation processes, making it a key intermediate for researchers in medicinal chemistry and synthetic organic chemistry.
- IUPAC
- tert-Butyl N-(3-piperidylmethyl)carbamate
- Synonyms
- tert-Butyl N-(3-piperidylmethyl)carbamate

Synthesis of Tylophorine Analogs
This compound is utilised as a reagent in the synthetic pathways leading to the preparation of Tylophorine analogs. These complex molecules are of interest in medicinal chemistry research.
Enzymatic Acylation Reactions
(±)-3-(Boc-aminomethyl)piperidine can be employed in enzymatic acylation processes. This application highlights its utility in biocatalytic transformations for selective chemical modifications.
Heterocyclic Building Block
As a substituted piperidine, it functions as a versatile heterocyclic building block. This makes it useful for introducing specific structural motifs into larger organic molecules during chemical synthesis.
| Molecular weight | 214.30 |
|---|---|
| Empirical formula | C11H22N2O2 |
| Assay | ≥98.0% (TLC) |
| Storage temperature | 2-8°C |
| Application | Reagent for: Preparation of Tylophorine analogs1 Enzymatic acylation2 |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3259PSN1 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (±)-3-(Boc-aminomethyl)piperidine used for?
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(±)-3-(Boc-aminomethyl)piperidine is used as a reagent in the preparation of Tylophorine analogs and in enzymatic acylation reactions. It is also a valuable building block in chemical synthesis, particularly for heterocyclic compounds.
What is the CAS number and formula for (±)-3-(Boc-aminomethyl)piperidine?
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The CAS number is 142643-29-6 and the empirical formula is C11H22N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (±)-3-(Boc-aminomethyl)piperidine with an assay of ≥98.0% (TLC). This is a research or technical grade chemical and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should (±)-3-(Boc-aminomethyl)piperidine be handled and stored?
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This compound is classified as Danger with hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including eyeshields, face shields, and chemical-resistant gloves, is essential. It should be stored at 2-8°C.
Is (±)-3-(Boc-aminomethyl)piperidine shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and reagents, including (±)-3-(Boc-aminomethyl)piperidine.
How can I request a quote or sample?
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To request a quote or sample of (±)-3-(Boc-aminomethyl)piperidine, please contact our sales department through the website or by phone.
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