3-(Boc-amino)propyl bromide
3-(Boc-amino)propyl bromide (CAS: 83948-53-2) is a valuable organic building block with the linear formula Br(CH2)3NHCO2C(CH3)3 and a molecular weight of 238.12 g/mol. This tert-butyl carbamate protected amine is often employed as a linker in chemical synthesis. It is suitable for use in research and development settings due to its defined reactivity, enabling specific modifications in complex molecular architectures.
- IUPAC
- tert-Butyl N-(3-bromopropyl)carbamate
- Synonyms
- tert-Butyl N-(3-bromopropyl)carbamate
Organic Synthesis
As a bifunctional linker, 3-(Boc-amino)propyl bromide is instrumental in introducing protected amino-propyl chains into molecules. The bromide serves as a leaving group for nucleophilic substitution reactions, while the Boc-protected amine can be deprotected under acidic conditions for further functionalization.
Chemical Biology Research
This compound can be utilised in the synthesis of bioconjugates and modified biomolecules. Its structure allows for controlled attachment to various scaffolds, facilitating studies in chemical biology and drug discovery.
Peptide Synthesis
3-(Boc-amino)propyl bromide can be incorporated into peptidomimetics or used to functionalise peptides with an aminoalkyl chain, enabling the creation of novel peptide-based therapeutics or research tools.
Materials Science
The molecule's dual functionality makes it a candidate for modifying surfaces or polymers, introducing specific chemical handles for advanced material applications.
| Molecular weight | 238.12 |
|---|---|
| Linear formula | Br(CH2)3NHCO2C(CH3)3 |
| Assay | ≥96.0% (GC) |
| Storage temperature | 2-8°C |
| Melting point | 37-39 °C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(Boc-amino)propyl bromide used for?
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3-(Boc-amino)propyl bromide is primarily used as a bifunctional linker and organic building block in chemical synthesis, particularly in areas like chemical biology, materials science, and the development of novel organic compounds.
What is the CAS number and formula for 3-(Boc-amino)propyl bromide?
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The CAS number is 83948-53-2 and the linear formula is Br(CH2)3NHCO2C(CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-(Boc-amino)propyl bromide with an assay of ≥96.0% (GC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety precautions for handling 3-(Boc-amino)propyl bromide?
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3-(Boc-amino)propyl bromide is classified as a Warning substance. It is harmful if swallowed, causes skin irritation, causes serious eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, in a well-ventilated area. Avoid breathing dust/fume/gas/mist/vapours/spray.
How is 3-(Boc-amino)propyl bromide packed and shipped?
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3-(Boc-amino)propyl bromide is typically stored at 2-8°C. Specific packing and shipping details for export are available upon request and comply with all relevant regulations.
How can I request a sample or quote for 3-(Boc-amino)propyl bromide?
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To request a sample or quote, please contact our sales department via the website or direct email, specifying the product CAS number 83948-53-2.
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