3-Aminothiophenol
3-Aminothiophenol (CAS: 22948-02-3), with the molecular formula H2NC6H4SH and a molecular weight of 125.19 g/mol, is a crucial organic building block. This sulfur-containing compound features both an amine and a thiol functional group. It is primarily utilised in chemical synthesis, including the formation of monolayers on metal surfaces and as an analyte in advanced material fabrication.
- IUPAC
- 3-Aminobenzenethiol
- Synonyms
- 3-Aminobenzenethiol

Surface Modification and Monolayer Formation
3-Aminothiophenol can anchor to gold surfaces via its thiol group, enabling the formation of self-assembled monolayers. This property is valuable for modifying surface characteristics in various advanced material applications.
Analyte in Material Fabrication
This compound has been employed as an analyte in the development of sophisticated material systems. For example, it was used in the fabrication of a joined system comprising silver nanowires and nanospheres.
Organic Synthesis Intermediate
As a bifunctional molecule containing both amine and thiol groups, 3-Aminothiophenol serves as a versatile intermediate in complex organic synthesis pathways.
| Molecular weight | 125.19 |
|---|---|
| Linear formula | H2NC6H4SH |
| Assay | 96% |
| Density | 1.179 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.656(lit.) |
| Application | 3-Aminothiophenol was used as analyte during the fabrication of top-to-bottom joined system consisting of a silver nanowire and nanospheres1. It was used in formation of polyaniline-analog monolayer on gold surface by anchoring to the gold substrate through the thiol moiety2. |


Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H314Causes severe skin burns and eye damage
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 79 °C / 174.2 °F |
| Transport (UN / ADR) | UN 3267 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 20/21/22-34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Aminothiophenol used for?
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3-Aminothiophenol is primarily used as a building block in chemical synthesis. It is also employed in forming polyaniline-analog monolayers on gold surfaces and as an analyte in material fabrication, such as in systems involving silver nanowires and nanospheres.
What are the CAS number and formula for 3-Aminothiophenol?
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The CAS number for 3-Aminothiophenol is 22948-02-3, and its linear formula is H2NC6H4SH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Aminothiophenol with an assay of 96%. We do not represent this product as USP, BP, or EP grade.
How should 3-Aminothiophenol be handled safely?
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3-Aminothiophenol is a hazardous substance. It is harmful if swallowed, in contact with skin, or if inhaled, and causes severe skin burns and eye damage. Appropriate personal protective equipment, including a full-face respirator, chemical-resistant gloves, and eye protection, should be used. Handle only in a well-ventilated area or under a fume hood.
Is 3-Aminothiophenol a controlled substance?
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The provided data does not indicate that 3-Aminothiophenol is a controlled substance.
How is 3-Aminothiophenol packed and shipped?
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3-Aminothiophenol is shipped under UN 3267, Class 8, Packing Group II. Specific packaging details can be provided upon request.
How can I request a sample or quote for 3-Aminothiophenol?
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To request a sample or a quotation for 3-Aminothiophenol, please contact our sales team through the website or by phone.
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