3-(Aminomethyl)-PROXYL
3-(Aminomethyl)-PROXYL (CAS 54606-49-4) is a stable nitroxide radical with the molecular formula C9H19N2O. This compound serves as a valuable spin label in biological systems and finds application in studying molecular diffusion. It has also demonstrated efficacy as a non-thiol radioprotector and is used in pharmacological research, including the inhibition of myeloperoxidase-mediated hypochlorous acid production. Its utility extends to reduction reactions and the synthesis of potential cardioprotectants.
- IUPAC
- 3-(Aminomethyl)-2,2,5,5-tetramethyl-1-pyrrolidinyloxy
Spin Labeling in Biological Systems
3-(Aminomethyl)-PROXYL is employed as a spin label to investigate the dynamics and environment within biological systems, providing insights into molecular interactions and structures.
Radioprotection Studies
The compound has been identified as an effective non-thiol radioprotector, suggesting its potential use in mitigating radiation damage in biological contexts.
Pharmacological Research
It is utilised in pharmacological studies, particularly in investigating the inhibition of hypochlorous acid production mediated by myeloperoxidase.
Chemical Synthesis
3-(Aminomethyl)-PROXYL participates in various chemical reactions, including reduction reactions with nitroxides and the synthesis of adenosine methycarboxamides with potential cardioprotective properties.
| Molecular weight | 171.26 |
|---|---|
| Empirical formula | C9H19N2O |
| Boiling point | 128-131 °C/13 mmHg(lit.) |
| Storage temperature | 2-8°C |
| Application | Useful spin label for studying biological systems.1,2 Used to study molecular diffusion into horse spleen ferritin3 and has been shown to be an effective nonthiol radioprotector.4,5Used in pharmacological studies of myeloperoxidase-mediated hypochlorous acid production inhibition6Reactant involved in: • Reduction reactions with nitroxides7• Synthesis of adenosine methycarboxamides for use as cardioprotectants8 |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 62 °C / 143.6 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(Aminomethyl)-PROXYL used for?
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3-(Aminomethyl)-PROXYL is a useful spin label for studying biological systems, investigated as a radioprotector, used in pharmacological studies of myeloperoxidase activity, and as a reactant in reduction reactions and synthesis of cardioprotectants.
What is the CAS number and formula for 3-(Aminomethyl)-PROXYL?
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The CAS number is 54606-49-4, and the empirical formula is C9H19N2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-(Aminomethyl)-PROXYL typically as a research or technical grade chemical. We do not represent this product as USP, BP, or EP grade unless explicitly stated in the product specifications.
How should 3-(Aminomethyl)-PROXYL be handled safely?
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3-(Aminomethyl)-PROXYL is harmful if swallowed, in contact with skin, or if inhaled, and causes skin and serious eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment including eyeshields, gloves, and a suitable respirator should be used. Handle in a well-ventilated area.
Is 3-(Aminomethyl)-PROXYL available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 3-(Aminomethyl)-PROXYL.
How can I request a quote or sample?
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Please contact our sales team directly through our website or by phone to request a quote or inquire about obtaining a sample of 3-(Aminomethyl)-PROXYL.
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