3-Amino-2-chloro-4-(trifluoromethyl)pyridine
3-Amino-2-chloro-4-(trifluoromethyl)pyridine (CAS: 166770-70-3; Formula: C6H4ClF3N2; Mol. Wt.: 196.56) is a fluorinated heterocyclic building block. It serves as a key intermediate in organic synthesis, particularly for the development of novel agrochemicals and pharmaceuticals. Its unique trifluoromethyl and halogenated pyridine structure makes it valuable for introducing specific functionalities into target molecules, enabling advanced chemical research and development.
- IUPAC
- 2-Chloro-4-(trifluoromethyl)-3-pyridinamine
Agrochemical Synthesis
This compound is utilised as a versatile building block in the synthesis of advanced agrochemicals. Its trifluoromethyl pyridine core can be incorporated into new pesticide and herbicide candidates, enhancing efficacy and stability.
Pharmaceutical Intermediates
It functions as a crucial intermediate in the development of active pharmaceutical ingredients (APIs). The compound's specific structural features are beneficial for designing drug candidates with targeted biological activity.
Organic Synthesis
As a functionalised pyridine derivative, it is employed in complex organic syntheses. Researchers leverage its reactivity to construct diverse molecular architectures for various chemical applications.
Fluorinated Compound Development
This chemical is instrumental in the creation of novel fluorinated organic compounds. The presence of the trifluoromethyl group allows for fine-tuning of physicochemical properties in new materials and molecules.
| Molecular weight | 196.56 |
|---|---|
| Empirical formula | C6H4ClF3N2 |
| Assay | 97% |
| Melting point | 53-57 °C |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Flash point | >110 °C / >230 °F |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Amino-2-chloro-4-(trifluoromethyl)pyridine used for?
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3-Amino-2-chloro-4-(trifluoromethyl)pyridine is primarily used as a building block in organic synthesis, particularly for the development of agrochemicals and pharmaceuticals. Its unique structure allows for the introduction of trifluoromethyl and halogenated pyridine moieties into target molecules.
What are the CAS number and formula for this compound?
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The CAS number is 166770-70-3, and its empirical formula (Hill notation) is C6H4ClF3N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with a minimum assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade; it is intended for research and development or technical applications.
How should 3-Amino-2-chloro-4-(trifluoromethyl)pyridine be handled safely?
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This compound is classified as Dangerous (GHS06, Danger). It is harmful if swallowed (H301), causes skin irritation (H315), may cause an allergic skin reaction (H317), causes serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area, avoiding contact with skin, eyes, and clothing. Refer to the Safety Data Sheet for detailed handling procedures.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions exports this chemical globally, adhering to all relevant shipping regulations. Packaging is designed to ensure product integrity and safety during transit, in accordance with UN 2811 classification for transport.
How can I request a sample or quote for 3-Amino-2-chloro-4-(trifluoromethyl)pyridine?
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To request a sample or quote, please contact our sales team through the website or by direct inquiry, providing your specific requirements and shipping details.
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