3,5-Dichlorobenzyl alcohol
3,5-Dichlorobenzyl alcohol (CAS: 60211-57-6), with the molecular formula C7H6Cl2O and a molecular weight of 177.03 g/mol, is a versatile organic building block. This compound serves as a key intermediate in various chemical synthesis pathways. Its utility is demonstrated in the preparation of specific nitriles and esters, making it valuable for researchers and manufacturers in the fine chemical and pharmaceutical sectors.
- Synonyms
- 3,5-Dichlorobenzyl alcoholCl2C6H3CH2OH
Preparation of Nitrile Compounds
3,5-Dichlorobenzyl alcohol can be converted to 3,5-dichlorophenylacetonitrile. This transformation typically involves reaction with thionyl chloride to form the corresponding benzyl chloride, followed by nucleophilic substitution with a cyanide salt.
Synthesis of Functionalised Esters
The compound has been utilised in the synthesis of complex esters, such as tert-butyl 2-cyano-3-(3,5-dichlorophenyl)-propanoate, via iridium-catalysed alkylation reactions with cyanoacetate derivatives.
Intermediate in Organic Synthesis
As a substituted benzyl alcohol, it functions as a valuable building block in the construction of more complex organic molecules, particularly in pharmaceutical and agrochemical research and development.
| Molecular weight | 177.03 |
|---|---|
| Linear formula | Cl2C6H3CH2OH |
| Assay | 98% |
| Application | 3,5-Dichlorobenzyl alcohol was used in the preparation of 3,5-dichlorophenylacetonitrile via reaction with boiling SOCl2, followed by reaction with NaCN1. It was also used in the synthesis of tert-butyl 2-cyano-3-(3,5-dichlorophenyl)-propanoate via Iridium-catalysed alkylation of tert-butyl cyanoacetate2. |
| Melting point | 79-82 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Dichlorobenzyl alcohol used for?
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3,5-Dichlorobenzyl alcohol is primarily used as an intermediate in organic synthesis for the preparation of compounds such as 3,5-dichlorophenylacetonitrile and functionalised esters used in research and development.
What are the CAS number and molecular formula for 3,5-Dichlorobenzyl alcohol?
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The CAS number is 60211-57-6, and the molecular formula is Cl2C6H3CH2OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,5-Dichlorobenzyl alcohol with a minimum assay of 98%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or any other pharmacopoeial grade.
How should 3,5-Dichlorobenzyl alcohol be handled safely?
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Handling should be done with appropriate personal protective equipment, including eyeshields and gloves. A respirator filter of type N95 (US) or P1 (EN143) is recommended. Refer to the Safety Data Sheet for comprehensive handling and hazard information.
Is 3,5-Dichlorobenzyl alcohol a controlled substance?
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The provided data does not indicate that 3,5-Dichlorobenzyl alcohol is a controlled substance.
How is 3,5-Dichlorobenzyl alcohol packed and shipped?
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Tech Serve Solutions exports chemicals globally, adhering to all relevant shipping regulations. Specific packaging details are available upon request.
How can I request a quote or sample for 3,5-Dichlorobenzyl alcohol?
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To request a quote or sample, please contact our sales department through the website or by phone, referencing the product name and CAS number 60211-57-6.
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