3,5-Di-tert-butylaniline
3,5-Di-tert-butylaniline (CAS: 2380-36-1) is an organic compound with the linear formula [(CH3)3C]2C6H3NH2 and a molecular weight of 205.34 g/mol. This aniline derivative, characterized by its bulky tert-butyl groups, serves as a valuable building block in organic synthesis. Its steric bulk influences reactivity and can be exploited in the creation of specialised molecules, particularly in the fields of chemical research and development.
- Synonyms
- [(CH3)3C]2C6H3NH2
![3,5-Di-tert-butylaniline ([(CH3)3C]2C6H3NH2) — chemical structure, CAS 2380-36-1; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F2380-36-1.png&w=3840&q=75)
Synthesis of Lipophilic Wedges
3,5-Di-tert-butylaniline is employed in the synthesis of lipophilic wedge structures. This application involves reacting the aniline derivative with other compounds, such as 2-amino-6-chloropyrimidin-4-ol, under specific reaction conditions like refluxing in acetic and hydrochloric acid.
Organic Building Block
As a key organic building block, this compound facilitates the construction of more complex molecular architectures. Its unique structural features, including the presence of two tert-butyl substituents, make it suitable for use in targeted chemical synthesis pathways.
Nitrogen Compound Synthesis
This aniline derivative falls under the category of nitrogen compounds, making it a useful starting material or intermediate in reactions where the introduction or modification of nitrogen-containing functionalities is required.
| Molecular weight | 205.34 |
|---|---|
| Linear formula | [(CH3)3C]2C6H3NH2 |
| Assay | 98% |
| Application | 3,5-Di-tert-butylaniline was used in the synthesis of lipophilic wedges by reacting with 2-amino-6-chloropyrimidin-4-ol in a refluxing mixture of acetic and hydrochloric acid1. |
| Melting point | 54-57 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Di-tert-butylaniline used for?
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3,5-Di-tert-butylaniline is primarily used as an organic building block in chemical synthesis, notably in the creation of lipophilic wedges. It is also a nitrogen compound suitable for various synthetic pathways.
What is the CAS number and formula for 3,5-Di-tert-butylaniline?
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The CAS number for 3,5-Di-tert-butylaniline is 2380-36-1, and its linear formula is [(CH3)3C]2C6H3NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,5-Di-tert-butylaniline with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 3,5-Di-tert-butylaniline be handled safely?
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3,5-Di-tert-butylaniline requires careful handling due to its irritant properties. Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. Refer to the safety data sheet for comprehensive handling guidelines.
Is 3,5-Di-tert-butylaniline a controlled substance?
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The provided data does not indicate that 3,5-Di-tert-butylaniline is a controlled substance.
How is 3,5-Di-tert-butylaniline packed and exported?
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Tech Serve Solutions exports fine chemicals globally. Specific packing details are available upon request, and shipments comply with international regulations for chemical transport.
How can I request a quote or sample for 3,5-Di-tert-butylaniline?
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To request a quote or sample, please contact our sales department through the website or by phone, providing the product name and CAS number (2380-36-1).
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