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3-(4-Fluorobenzoyl)propionic acid

CAS 366-77-8FC6H4COCH2CH2CO2HChemical Synthesis

3-(4-Fluorobenzoyl)propionic acid (CAS 366-77-8) is a fluorinated organic building block with the linear formula FC<sub>6</sub>H<sub>4</sub>COCH<sub>2</sub>CH<sub>2</sub>CO<sub>2</sub>H and a molecular weight of 196.18 g/mol. This carboxylic acid is valuable in chemical synthesis, particularly for introducing fluorobenzoylpropionic acid moieties into more complex molecules. It serves as an intermediate in the development of various chemical compounds, leveraging the unique properties conferred by the fluorine atom and the ketone and carboxylic acid functional groups.

IUPAC
Haloperidol metabolite III,R 11302
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3-(4-Fluorobenzoyl)propionic acid (FC6H4COCH2CH2CO2H) — chemical structure, CAS 366-77-8; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksC10C8-C12Carbonyl CompoundsCarboxylic AcidsChemical SynthesisFluorinated Building BlocksOrganic Building Blocks
01 /Applications

Intermediate in Organic Synthesis

Utilised as a key building block in multi-step organic syntheses, facilitating the creation of novel chemical entities. Its structure allows for versatile functionalisation.

Fluorinated Compound Development

A precursor for synthesising more complex fluorinated organic compounds. The presence of fluorine can significantly alter a molecule's physical and biological properties.

Pharmaceutical Research

Serves as a starting material or intermediate in the research and development of potential pharmaceutical agents, where fluorinated motifs are often employed to enhance efficacy or metabolic stability.

Material Science

Can be employed in the synthesis of specialised polymers or materials where its specific structural features are desired.

02 /Properties
Molecular weight196.18
Linear formulaFC6H4COCH2CH2CO2H
Assay97%
Melting point100-102 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H302Harmful if swallowed
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn
Risk statements (R)22

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
366-77-8
MDL number
MFCD00002793
PubChem substance
24850580
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3-(4-Fluorobenzoyl)propionic acid used for?

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3-(4-Fluorobenzoyl)propionic acid is primarily used as a versatile building block in organic synthesis, particularly for developing fluorinated organic compounds and as an intermediate in pharmaceutical research.

What are the CAS number and formula for 3-(4-Fluorobenzoyl)propionic acid?

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The CAS number is 366-77-8 and the linear formula is FC<sub>6</sub>H<sub>4</sub>COCH<sub>2</sub>CH<sub>2</sub>CO<sub>2</sub>H.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 3-(4-Fluorobenzoyl)propionic acid with an assay of 97%. We do not represent this product as USP, BP, EP or other pharmacopoeial grades unless explicitly stated in the specifications.

How should 3-(4-Fluorobenzoyl)propionic acid be handled safely?

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3-(4-Fluorobenzoyl)propionic acid is classified as harmful if swallowed (H302). Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation.

Is 3-(4-Fluorobenzoyl)propionic acid a controlled substance?

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Based on the provided data, there is no indication that 3-(4-Fluorobenzoyl)propionic acid is a controlled substance.

How is this chemical packed, shipped, and exported?

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Tech Serve Solutions packs, ships, and exports chemicals globally, adhering to all relevant safety and regulatory standards for hazardous materials.

How can I request a sample or quote for 3-(4-Fluorobenzoyl)propionic acid?

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To request a sample or quote, please contact our sales team through the website or by phone, providing the product name and CAS number.

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