3,4-Dichlorobenzenethiol
3,4-Dichlorobenzenethiol (CAS: 5858-17-3) is an organosulfur compound with the linear formula Cl2C6H3SH and a molecular weight of 179.07 g/mol. This chemical serves as a valuable building block in organic synthesis and is employed as a trapping agent for electrophiles. It has been utilised in detecting methylating agent production and as a component in developing advanced sensors.
- Synonyms
- 5858-17-3Cl2C6H3SH
Electrophile Trapping Agent
3,4-Dichlorobenzenethiol is used as a trapping agent for electrophiles produced both in vitro and in vivo. This application is crucial for studying metabolic pathways and reactive intermediates in biological systems.
Methylating Agent Detection
This compound was employed as a probe for the detection of methylating agent production during the exposure of N-nitrosodimethylamine to rat liver S-9 preparations, aiding in toxicological research.
Sensor Development
It has been incorporated into the development of surface-enhanced Raman sensors, demonstrating utility in detecting specific analytes such as biowarfare agents and glucose.
| Molecular weight | 179.07 |
|---|---|
| Linear formula | Cl2C6H3SH |
| Assay | 97% |
| Boiling point | 119-120 °C/10 mmHg(lit.) |
| Density | 1.407 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.623(lit.) |
| Application | 3,4-Dichlorobenzenethiol was employed as probe for detection of methylating agent production during exposure of N-nitrosodimethylamine to rat liver S-9 preparations1. It was used as trapping agent for electrophiles produced in vitro or in vivo1. It was used to develop surface-enhanced Raman sensor for detection of biowarfare agent and glucose2. |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >113 °C / >235.4 °F |
| Transport (UN / ADR) | UN 3334 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4-Dichlorobenzenethiol used for?
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3,4-Dichlorobenzenethiol is used as a building block in chemical synthesis, as a trapping agent for electrophiles, for detecting methylating agent production, and in the development of surface-enhanced Raman sensors.
What are the CAS number and chemical formula for 3,4-Dichlorobenzenethiol?
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The CAS number is 5858-17-3, and its linear formula is Cl2C6H3SH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,4-Dichlorobenzenethiol with an assay of 97%. This is typically a technical or research grade, and TSS does not represent it as USP, BP, or EP grade unless explicitly stated.
How should 3,4-Dichlorobenzenethiol be handled safely?
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3,4-Dichlorobenzenethiol is a hazardous substance. It is harmful if swallowed, causes skin irritation, causes serious eye damage, and may cause respiratory irritation. Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, should be used. Consult the Safety Data Sheet for detailed handling procedures.
Is 3,4-Dichlorobenzenethiol a controlled substance?
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The provided data does not indicate that 3,4-Dichlorobenzenethiol is a controlled substance.
How can I request a quote or sample for 3,4-Dichlorobenzenethiol?
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Please contact the TSS sales team directly through our website or by phone to request a quote or sample.
How is 3,4-Dichlorobenzenethiol packed and shipped?
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3,4-Dichlorobenzenethiol is packed according to industry standards for hazardous materials and is available for export. Specific packaging and shipping details can be provided upon request.
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