3,3′-Methylene-bis(4-hydroxycoumarin)
3,3′-Methylene-bis(4-hydroxycoumarin) (CAS 66-76-2) is an organic compound with the molecular formula C19H12O6 and a molecular weight of 336.29 g/mol. This chemical serves as a valuable intermediate and reagent in various chemical syntheses. It is recognised for its applications in biological research, particularly in areas related to cell biology and hematology.
- IUPAC
- Dicoumarol,Dicumarol
- Synonyms
- DicoumarolDicumarol

Biological Staining and Histology
Utilised as a stain or dye in histological and hematological preparations to aid in microscopic examination of tissues and blood samples.
Cell Biology Research
Employed as a tool in cell biology studies, potentially for investigating cellular processes or as a component in specific assays.
Chemical Synthesis Intermediate
Serves as a building block in the synthesis of more complex organic molecules, leveraging its unique coumarin structure.
| Molecular weight | 336.29 |
|---|---|
| Empirical formula | C19H12O6 |
| Melting point | 290-292 °C(lit.) |



Hazard statements
- H302Harmful if swallowed
- H372Causes damage to organs through prolonged exposure
- H411Toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P314Get medical attention if you feel unwell
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 22-48/25-51/53 |
| Safety statements (S) | 37-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CYP2C9(1559) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,3′-Methylene-bis(4-hydroxycoumarin) used for?
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3,3′-Methylene-bis(4-hydroxycoumarin) is used in biological staining, histology, cell biology research, and as an intermediate in chemical synthesis.
What are the CAS number and formula for 3,3′-Methylene-bis(4-hydroxycoumarin)?
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The CAS number is 66-76-2 and the empirical formula is C19H12O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical as a technical or research grade. We do not represent it as USP, BP, or EP grade.
What are the safety considerations for handling 3,3′-Methylene-bis(4-hydroxycoumarin)?
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This compound presents significant hazards, including H302 (Harmful if swallowed), H372 (Causes damage to organs through prolonged or repeated exposure), and H411 (Toxic to aquatic life with long lasting effects). Appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a P2 respirator, must be used. Handle with extreme care in a well-ventilated area.
How is 3,3′-Methylene-bis(4-hydroxycoumarin) packed, shipped, and exported?
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As a global supplier, Tech Serve Solutions professionally packs, ships, and exports chemicals worldwide, adhering to all relevant regulations for hazardous materials, including UN 2811 classification.
How can I request a sample or quote for 3,3′-Methylene-bis(4-hydroxycoumarin)?
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Please contact our sales department via the website or direct email to request a sample or a formal quotation for 3,3′-Methylene-bis(4-hydroxycoumarin).
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