3,3-Dimethylacryloyl chloride
3,3-Dimethylacryloyl chloride (CAS 3350-78-5), molecular formula (CH3)2C=CHCOCl, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to pharmacopoeia specification (USP, BP, EP). Every batch is tested and ships with a Certificate of Analysis; MSDS and technical data sheets are available on request. Tech Serve Solutions has supplied laboratory reagents, fine chemicals and pharmaceutical intermediates worldwide since 1998.
- IUPAC
- 3-Methyl-2-butenoyl chloride,3-Methylcrotonoyl chloride,Senecioyl chloride

| Molecular weight | 118.56 |
|---|---|
| Linear formula | (CH3)2C=CHCOCl |
| Assay | 97% |
| Boiling point | 145-147 °C(lit.) |
| Density | 1.065 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.476(lit.) |
| Contains / stabiliser | 400 ppm phenothiazine as inhibitor |
| Application | 3,3-Dimethylacryloyl chloride was used in the synthesis of:• substituted 4,4-dimethyl-3,4-dihydro-1H-quinolin-2-one via condensation with aniline1• N-(3,3-Dimethylacryloyl)-(S)-leucine methyl ester2 |



Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 51 °C / 123.8 °F |
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 14-34-36/37 |
| Safety statements (S) | 26-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Supplied to USP, BP and EP standards. Every batch ships with a Certificate of Analysis (assay, identity, purity); MSDS and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,3-Dimethylacryloyl chloride?
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3,3-Dimethylacryloyl chloride (CAS 3350-78-5), molecular formula (CH3)2C=CHCOCl, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to USP, BP and EP standards.
What grades of 3,3-Dimethylacryloyl chloride does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,3-Dimethylacryloyl chloride in USP, BP, EP and reagent/AR grades. Custom specifications for nutraceutical or specialty pharmaceutical applications are available — contact our technical sales team.
What is the CAS number and molecular formula of 3,3-Dimethylacryloyl chloride?
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3,3-Dimethylacryloyl chloride has CAS number 3350-78-5 and molecular formula (CH3)2C=CHCOCl. Full specifications appear in the table above and in the Certificate of Analysis.
What is the typical minimum order quantity and lead time for 3,3-Dimethylacryloyl chloride?
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Sample quantities are available for technical evaluation; bulk MOQ depends on grade and packaging. In-stock material typically ships in 7–10 working days; custom-spec orders take 3–4 weeks. Tech Serve Solutions ships worldwide with full export documentation.
Do you provide a Certificate of Analysis (CoA) with each shipment?
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Yes. Every batch of 3,3-Dimethylacryloyl chloride ships with a Certificate of Analysis covering assay, identity and purity tests, plus pharmacopoeia conformance where applicable. MSDS and TDS documents are available on request before order placement.
How should 3,3-Dimethylacryloyl chloride be stored?
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Store 3,3-Dimethylacryloyl chloride in its original sealed container in a cool, dry place away from direct sunlight and incompatible materials, in line with the storage guidance on the Safety Data Sheet. Reseal between dispensings.
What is 3,3-Dimethylacryloyl chloride used for?
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3,3-Dimethylacryloyl chloride is used in chemical synthesis applications across pharmaceutical, research and industrial settings. Our technical team can advise on suitability for your specific process.
How do I request a quote for 3,3-Dimethylacryloyl chloride?
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Request a quote with your required grade, quantity and destination via https://www.techservesolutions.in/contact or email info@techservesolutions.in. We respond with specifications, a Certificate of Analysis and pricing.
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