(2S,3S)-Hydroxybupropion hydrochloride

CAS 106083-71-0C13H18ClNO2 · HClBiochemicals & Reagents

(2S,3S)-Hydroxybupropion hydrochloride (CAS: 106083-71-0) is a chemical compound with a molecular weight of 292.20 g/mol. It presents as a white to tan powder. This substance is primarily utilised in scientific research, particularly within the fields of cell biology, neuroscience, and neuropharmacology. Its role as a bioactive small molecule makes it a valuable tool for investigating neurotransmitter transport mechanisms and related cellular processes.

IUPAC: (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol hydrochloride,(2S,3S)-2-(3-Chlorophenyl)-3,5,5-trimethyl-2-morpholinol hydrochloride,(2S,3S)-Hydroxybupropion hydrochloride,GW 353162,Radafaxine hydrochloride,SS-hydroxybupropion hydrochloride
Synonyms: (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol hydrochloride(2S,3S)-2-(3-Chlorophenyl)-3,5,5-trimethyl-2-morpholinol hydrochlorideGW 353162Radafaxine hydrochlorideSS-hydroxybupropion hydrochloride

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(2S,3S)-Hydroxybupropion hydrochloride (C13H18ClNO2 · HCl) — chemical structure, CAS 106083-71-0; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesBiochemicals and ReagentsCell BiologyGPCR ModulatorsGPCR ProteinsModulators and AntibodiesNeuroscienceNeurotransmissionNeurotransmitters

01 /Applications

Neuroscience Research

(2S,3S)-Hydroxybupropion hydrochloride serves as a critical reagent in neuroscience research. It is used to study the mechanisms of neurotransmitter reuptake and their influence on neuronal signalling pathways.

Cell Biology Studies

In cell biology, this compound is employed to investigate cellular processes affected by biogenic amine transport. It aids in understanding the functional roles of various transporters within cell membranes.

Biochemical Assays

As a biochemical reagent, (2S,3S)-Hydroxybupropion hydrochloride is valuable for conducting assays related to neurotransmission and GPCR modulation. Its specific stereochemistry can be important for selective biological activity.

02 /Properties

Molecular weight	292.20
Empirical formula	C13H18ClNO2 · HCl
Assay	≥98% (HPLC)
Form	powder
Colour	white to tan
Solubility	DMSO: ≥12 mg/mL
Storage temperature	−20°C

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305IF IN EYES

Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36
Safety statements (S)	26

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

106083-71-0

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (2S,3S)-Hydroxybupropion hydrochloride used for?

(2S,3S)-Hydroxybupropion hydrochloride is used in scientific research, particularly in neuroscience and cell biology, to study neurotransmitter transport and related cellular signalling pathways.

What is the CAS number and formula for (2S,3S)-Hydroxybupropion hydrochloride?

The CAS number is 106083-71-0 and the empirical formula is C13H18ClNO2 · HCl.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (2S,3S)-Hydroxybupropion hydrochloride with an assay of ≥98% (HPLC). This product is not supplied as USP, BP, EP, or other pharmacopoeia grade.

How should (2S,3S)-Hydroxybupropion hydrochloride be handled?

Caution is advised as (2S,3S)-Hydroxybupropion hydrochloride is an irritant. Wear eye protection, protective clothing, and gloves. In case of contact with eyes, rinse cautiously with water for several minutes and seek medical advice if irritation persists. Ensure adequate ventilation.

How is (2S,3S)-Hydroxybupropion hydrochloride shipped and stored?

This compound is stored at -20°C. TSS exports fine chemicals globally, adhering to all necessary regulations for safe and compliant international shipping.