20-Deoxy-20-oxophorbol 12-myristate 13-acetate
20-Deoxy-20-oxophorbol 12-myristate 13-acetate (CAS: 30358-69-1) is an organic compound with the molecular formula C36H54O8. This phorbol derivative serves as a valuable chemical intermediate, primarily utilised in biochemical research. Its specific structural features allow for its use in the synthesis of radiolabelled compounds, which are essential tools for investigating biological pathways and receptor interactions within cellular systems.
Synthesis of Radiolabelled Compounds
Reduction with tritiated sodium borohydride (NaBH4) yields tritiated phorbol 12-myristate 13-acetate. This radiolabelled derivative is useful for receptor binding studies, enabling researchers to quantify and study the binding affinity and kinetics of phorbol esters to their biological targets.
Biochemical Research Intermediate
As a phorbol ester derivative, it can be employed as a building block or tool compound in various biochemical research applications. Its availability supports studies in cell signalling, protein kinase C (PKC) research, and other areas where phorbol derivatives are investigated.
Organic Synthesis
The molecule can serve as a starting material or intermediate in complex organic synthesis pathways. Its functional groups allow for further chemical modification, leading to the creation of novel compounds with potential biological activities or for materials science applications.
| Molecular weight | 614.81 |
|---|---|
| Empirical formula | C36H54O8 |
| Storage temperature | −20°C |
| Application | Reduction with tritiated NaBH4 yields tritiated phorbol 12-myristate 13-acetate that can be used for receptor binding studies |
Hazard statements
- H300Fatal if swallowed
- H310Fatal in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H330Fatal if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P302IF ON SKIN
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 26/27/28-36/37/38 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 20-Deoxy-20-oxophorbol 12-myristate 13-acetate used for?
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This compound is primarily used in biochemical research, particularly for the synthesis of radiolabelled derivatives for receptor binding studies. It also serves as a valuable intermediate in organic synthesis and general biochemical research.
What is the CAS number and molecular formula for 20-Deoxy-20-oxophorbol 12-myristate 13-acetate?
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The CAS number is 30358-69-1, and the molecular formula is C36H54O8.
What grade and purity does Tech Serve Solutions supply for 20-Deoxy-20-oxophorbol 12-myristate 13-acetate?
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Tech Serve Solutions supplies this product for research and development purposes. The specific assay and purity are detailed in the product's Certificate of Analysis. We do not represent this product as meeting USP, BP, EP, or other pharmacopoeial standards.
What are the safety considerations when handling 20-Deoxy-20-oxophorbol 12-myristate 13-acetate?
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This compound is classified as acutely toxic and an irritant. It carries the GHS signal word 'Danger' with hazard statements H300 (Fatal if swallowed), H310 (Fatal in contact with skin), H315 (Causes skin irritation), H319 (Causes serious eye irritation), H330 (Fatal if inhaled), and H335 (May cause respiratory irritation). Always use appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, and handle in a well-ventilated area or fume hood.
How is 20-Deoxy-20-oxophorbol 12-myristate 13-acetate typically packed and shipped?
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Our chemicals are carefully packed according to international shipping regulations to ensure safe transit. For specific packaging details or international export inquiries, please contact our sales team.
How can I request a sample or a quote for 20-Deoxy-20-oxophorbol 12-myristate 13-acetate?
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To request a sample or a quote, please use the 'Contact Us' form on our website or contact our customer service department directly with your inquiry, referencing the product name and CAS number.
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