2-(Tributylstannyl)pyrazine
2-(Tributylstannyl)pyrazine (CAS 205371-27-3) is an organotin compound with a molecular weight of 369.13. It functions as a valuable reagent in organic synthesis, specifically for palladium-catalyzed cross-coupling reactions. This compound is primarily utilised in the microwave-assisted synthesis of substituted pyranones, demonstrating its utility in advanced synthetic methodologies for creating complex heterocyclic structures.
- IUPAC
- (2-Pyrazinyl)tributyltin,Tributylstannylpyrazine
- Synonyms
- (2-Pyrazinyl)tributyltinTributylstannylpyrazine
![2-(Tributylstannyl)pyrazine ((C4H3N2)Sn[(CH2)3CH3]3) — chemical structure, CAS 205371-27-3; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F205371-27-3.png&w=3840&q=75)
Palladium-Catalyzed Cross-Coupling Reactions
Utilised as an organotin coupling partner in palladium-catalyzed cross-coupling reactions. This is particularly effective for the synthesis of substituted pyranones from arylstannanes and pyranyl triflates.
Microwave-Assisted Synthesis
Facilitates microwave-assisted synthetic routes, enabling efficient and rapid formation of target molecules. This method is applied in the construction of substituted pyranone derivatives.
Synthesis of Heterocyclic Compounds
Serves as a building block for the synthesis of various heterocyclic compounds, including pyranone structures, which are important motifs in medicinal chemistry and materials science.
| Molecular weight | 369.13 |
|---|---|
| Linear formula | (C4H3N2)Sn[(CH2)3CH3]3 |
| Assay | 95% |
| Boiling point | 130 °C/1 mmHg |
| Density | 1.1706 g/mL at 25 °C |
| Refractive index | n20/D 1.5158 |
| Storage temperature | −20°C |
| Application | Microwave-assisted synthesis of substituted pyranones by palladium-catalyzed cross-coupling of arylstannanes with pyranyl triflates.1 |
Hazard statements
- H301Toxic if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H372Causes damage to organs through prolonged exposure
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P314Get medical attention if you feel unwell
- P501Dispose of contents and container per local regulations
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >113 °C / >235.4 °F |
| Transport (UN / ADR) | UN 2788 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 21-25-36/38-48/23/25-50/53 |
| Safety statements (S) | 35-36/37/39-45-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Tributylstannyl)pyrazine used for?
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2-(Tributylstannyl)pyrazine is used as a reagent in palladium-catalyzed cross-coupling reactions, notably in the microwave-assisted synthesis of substituted pyranones.
What is the CAS number and formula for 2-(Tributylstannyl)pyrazine?
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The CAS number is 205371-27-3 and the linear formula is (C4H3N2)Sn[(CH2)3CH3]3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Tributylstannyl)pyrazine with an assay of 95%. This product is supplied for research and development purposes and TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-(Tributylstannyl)pyrazine be handled safely?
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This compound is classified as Danger, with hazards including toxicity (H301, H312, H372) and irritation (H315, H319), and is very toxic to aquatic life with long-lasting effects (H410). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area. Refer to the Safety Data Sheet for comprehensive handling and emergency procedures.
How is 2-(Tributylstannyl)pyrazine packed and shipped?
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2-(Tributylstannyl)pyrazine is packed and shipped in accordance with international regulations for hazardous materials (UN 2788, 6.1, PGII). As a global supplier, Tech Serve Solutions exports this chemical worldwide.
How can I request a quote or sample of 2-(Tributylstannyl)pyrazine?
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To request a quote or sample, please contact our sales team through the website or by calling our direct line. Specify the product name and CAS number (205371-27-3) in your request.
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