2-Nitrothiophene
2-Nitrothiophene (CAS: 609-40-5; Formula: C4H3NO2S; MW: 129.14 g/mol) is a heterocyclic organic compound featuring a thiophene ring substituted with a nitro group. This compound is primarily recognised as a valuable building block in organic synthesis, particularly within the C4 to C6 and heterocyclic chemical domains. It serves as a key intermediate for the creation of more complex molecules and speciality chemicals.

Organic Synthesis Intermediate
2-Nitrothiophene functions as a versatile intermediate in the synthesis of diverse organic compounds. Its reactive nitro group and thiophene core enable participation in various chemical transformations.
Heterocyclic Chemistry
As a substituted thiophene, this compound is instrumental in the construction of more complex heterocyclic systems. It is used in research and development for novel material and pharmaceutical agents.
Fine Chemical Production
It is employed in the manufacture of fine chemicals where the thiophene moiety is a desired structural element. Applications can range from dyestuffs to speciality polymers.
| Molecular weight | 129.14 |
|---|---|
| Empirical formula | C4H3NO2S |
| Assay | 85% |
| Boiling point | 224-225 °C(lit.) |
| Impurities tested | 15% 3-nitrothiophene |
| Melting point | 43-45 °C(lit.) |
| Flash point | 94 °C / 201.2 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Nitrothiophene used for?
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2-Nitrothiophene is primarily used as a building block and intermediate in organic synthesis, particularly for creating complex heterocyclic compounds and fine chemicals.
What is the CAS number and molecular formula for 2-Nitrothiophene?
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The CAS number for 2-Nitrothiophene is 609-40-5, and its molecular formula is C4H3NO2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Nitrothiophene with an assay of 85%, containing approximately 15% 3-nitrothiophene as an impurity. This product is supplied for research and development or technical use; TSS does not represent it as USP, BP, or EP grade.
What are the safety and handling precautions for 2-Nitrothiophene?
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2-Nitrothiophene is classified under GHS with relevant hazards. It is combustible with a flash point of 94°C (201.2°F). Handle with appropriate personal protective equipment in a well-ventilated area. Consult the Safety Data Sheet (SDS) for detailed information.
How is 2-Nitrothiophene packed, shipped, and exported?
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2-Nitrothiophene is carefully packed according to regulatory standards for chemicals of its class. Tech Serve Solutions offers global export services, adhering to all international shipping and customs regulations for chemical products.
How can I request a quote or sample for 2-Nitrothiophene?
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To request a quote or obtain a sample of 2-Nitrothiophene, please contact our sales department through the website or by phone, providing your specific requirements and shipping details.
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