2-Nitrobenzenesulfonyl chloride
2-Nitrobenzenesulfonyl chloride (CAS: 1694-92-4, Formula: O2NC6H4SO2Cl) is a crucial organic intermediate with a molecular weight of 221.62 g/mol. This compound serves as a valuable building block in chemical synthesis, particularly in the preparation of more complex molecules within organic and medicinal chemistry research. Its reactive sulfonyl chloride group enables various derivatisation reactions.

Organic Synthesis Reagent
Utilised as a building block for constructing diverse organic molecules. Its sulfonyl chloride functionality allows for reactions such as sulfonamide and sulfonate ester formation.
Intermediate in Pharmaceutical Research
Serves as a key intermediate in the synthesis pathways for potential pharmaceutical compounds and drug discovery programmes. It aids in the introduction of the nitrobenzenesulfonyl moiety.
Chemical Research and Development
Employed in academic and industrial R&D settings for exploring new chemical transformations and synthesising novel compounds. Its reactivity profile makes it a versatile tool.
| Molecular weight | 221.62 |
|---|---|
| Linear formula | O2NC6H4SO2Cl |
| Assay | 97% |
| Melting point | 63-67 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Nitrobenzenesulfonyl chloride used for?
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2-Nitrobenzenesulfonyl chloride (CAS: 1694-92-4) is primarily used as a building block in organic synthesis and as an intermediate in pharmaceutical research and chemical R&D.
What are the CAS number and molecular formula for 2-Nitrobenzenesulfonyl chloride?
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The CAS number is 1694-92-4, and the molecular formula is O2NC6H4SO2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Nitrobenzenesulfonyl chloride with an assay of 97%. This is a technical/research grade material and is not represented as USP, BP, or EP grade.
How should 2-Nitrobenzenesulfonyl chloride be handled safely?
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2-Nitrobenzenesulfonyl chloride is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection (e.g., N100 or P3 filters), is essential. Handle in a well-ventilated area.
Can Tech Serve Solutions export 2-Nitrobenzenesulfonyl chloride?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Nitrobenzenesulfonyl chloride, adhering to all relevant international shipping regulations.
How can I request a quote or sample for 2-Nitrobenzenesulfonyl chloride?
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To request a quote or sample, please contact our sales department via the website or directly by phone. Our team will assist you promptly.
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