2-Nitro-4-(trifluoromethyl)benzaldehyde
2-Nitro-4-(trifluoromethyl)benzaldehyde (CAS: 109466-87-7, C8H4F3NO3) is a trifluoromethylated benzaldehyde derivative with a molecular weight of 219.12 g/mol. This compound functions as a valuable intermediate in organic synthesis, particularly for the preparation of more complex molecules. Its structure, featuring both a nitro group and a trifluoromethyl group adjacent to the aldehyde, makes it a useful building block in medicinal chemistry and materials science research.

Intermediate in Organic Synthesis
Serves as a key building block for the synthesis of pharmaceuticals, agrochemicals, and specialty materials. The presence of reactive functional groups allows for diverse chemical transformations.
Medicinal Chemistry Research
Utilised in the development of novel therapeutic agents. The trifluoromethyl moiety is often incorporated to enhance metabolic stability and lipophilicity of drug candidates.
Materials Science
Can be employed in the creation of functional organic materials due to its unique electronic and structural properties imparted by the nitro and trifluoromethyl substituents.
| Molecular weight | 219.12 |
|---|---|
| Empirical formula | C8H4F3NO3 |
| Assay | 97% |
| Melting point | 41-45 °C |

Hazard statements
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36-43 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Nitro-4-(trifluoromethyl)benzaldehyde used for?
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2-Nitro-4-(trifluoromethyl)benzaldehyde (CAS: 109466-87-7) is primarily used as an intermediate in organic synthesis, particularly in medicinal chemistry and materials science for the preparation of more complex molecules.
What is the CAS number and chemical formula for 2-Nitro-4-(trifluoromethyl)benzaldehyde?
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The CAS number is 109466-87-7, and the chemical formula is C8H4F3NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Nitro-4-(trifluoromethyl)benzaldehyde with a typical assay of 97%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or any other pharmacopoeial grade.
What are the primary safety concerns when handling this chemical?
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This compound is classified with GHS07 symbol and a Warning signal word. It may cause an allergic skin reaction (H317) and causes serious eye irritation (H319). Appropriate personal protective equipment, including dust mask type N95 (US), eyeshields, faceshields, and gloves, should be used. Handle in a well-ventilated area.
Is this product available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Nitro-4-(trifluoromethyl)benzaldehyde. We ship products worldwide.
How can I request a sample or a quote?
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To request a sample or a quote for 2-Nitro-4-(trifluoromethyl)benzaldehyde, please visit our website or contact our sales team directly through the provided channels.
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