2-Naphthoyl chloride
2-Naphthoyl chloride (CAS 2243-83-6) is an organic compound with the linear formula C11H7ClO and a molecular weight of 190.63 g/mol. As an acid halide, it serves as a valuable building block in organic synthesis. This compound is primarily utilised in the preparation of various amide derivatives and other complex organic molecules, contributing to advancements in chemical research and development.
- IUPAC
- β-Naphthoyl chloride
- Synonyms
- β-Naphthoyl chloride
Synthesis of Amide Derivatives
2-Naphthoyl chloride is employed in the preparation of amide derivatives. For example, it has been used in the synthesis of amide derivatives of amphetamine enantiomers, contributing to chiral chemistry research.
Preparation of Heterocyclic Compounds
This compound serves as a precursor in the synthesis of specific heterocyclic structures. Its reactivity allows for the formation of complex molecules, such as the synthesis of 7-dimethylamino-2-methyl-3-naphthamido-phenothiaziniun salt.
Surface Modification
2-Naphthoyl chloride can be utilised for modifying surfaces. It has been applied in the modification of self-assembled monolayers formed on silica surfaces, enabling tailored material properties.
| Molecular weight | 190.63 |
|---|---|
| Linear formula | C10H7COCl |
| Assay | ≥98.0% (GC) |
| Boiling point | 160-162 °C/11 mmHg(lit.) |
| Storage temperature | 2-8°C |
| Application | 2-Naphthoyl chloride has been used in:• preparation of amide derivatives of the amphetamine enantiomers1• synthesis of 7-dimethylamino-2-methyl-3-naphthamido-phenothiazinium salt2• modification of self-assembled monolayer formed on silica surface from ((((aminoethyl)amino)-methyl)phenethyl)trimethoxysilane3 |
| Melting point | 50-52 °C(lit.)50-52 °C |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Naphthoyl chloride used for?
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2-Naphthoyl chloride is used as a building block in organic synthesis, including the preparation of amide derivatives and complex organic molecules. It has also been employed in surface modification applications.
What is the CAS number and formula for 2-Naphthoyl chloride?
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The CAS number for 2-Naphthoyl chloride is 2243-83-6, and its linear formula is C11H7ClO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Naphthoyl chloride with an assay of ≥98.0% (GC). This is a technical/research grade, and TSS does not represent it as USP, BP, or EP grade.
How should 2-Naphthoyl chloride be handled safely?
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2-Naphthoyl chloride is classified as corrosive (H314). Handle with appropriate personal protective equipment, including eyeshields, faceshields, gloves, and suitable respiratory protection. Always consult the Safety Data Sheet (SDS) before use.
How is 2-Naphthoyl chloride packed, shipped, and exported?
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2-Naphthoyl chloride is packed securely for transport. As a global supplier, Tech Serve Solutions exports chemicals adhering to international shipping regulations for hazardous materials.
How can I request a sample or quote for 2-Naphthoyl chloride?
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To request a sample or quote for 2-Naphthoyl chloride, please contact the Tech Serve Solutions sales team via the website or listed contact details.
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