(2-Naphthalenylmethyl)magnesium bromide solution
(2-Naphthalenylmethyl)magnesium bromide solution (CAS: 127543-80-0) is an organometallic compound with a molecular weight of 245.40. Supplied as a solution, typically in diethyl ether, it functions as a reactive Grignard reagent. This compound is valuable in organic synthesis for introducing the 2-naphthalenylmethyl group into various molecules, facilitating the construction of more complex organic structures.
Grignard Reagent in Organic Synthesis
This magnesium bromide solution serves as a versatile Grignard reagent. It is employed to form new carbon-carbon bonds by reacting with electrophiles such as aldehydes, ketones, and esters.
Introduction of the 2-Naphthalenylmethyl Moiety
The reagent is specifically useful for the alkylation of organic substrates with the 2-naphthalenylmethyl group. This is a key step in the synthesis of various naphthalene-containing compounds.
Intermediate in Pharmaceutical Research
Compounds derived from reactions involving (2-Naphthalenylmethyl)magnesium bromide may serve as intermediates in the development of novel pharmaceutical agents, leveraging the structural properties of the naphthalene core.
| Molecular weight | 245.40 |
|---|---|
| Empirical formula | C11H9BrMg |
| Density | 0.776 g/mL at 25 °C |
| Concentration | 0.25 M in diethyl ether |
Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H336May cause drowsiness or dizziness
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -30 °C / -22 °F |
| Transport (UN / ADR) | UN 2924 8(3) / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-22-36/38-67 |
| Safety statements (S) | 16-26 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2-Naphthalenylmethyl)magnesium bromide solution used for?
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(2-Naphthalenylmethyl)magnesium bromide solution is used as a Grignard reagent in organic synthesis to introduce the 2-naphthalenylmethyl group into molecules and form new carbon-carbon bonds.
What are the CAS number and formula for (2-Naphthalenylmethyl)magnesium bromide solution?
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The CAS number is 127543-80-0. The empirical formula (Hill notation) is C11H9BrMg.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a 0.25 M solution in diethyl ether. We do not claim USP, BP, or EP grade; it is suitable for research and chemical synthesis purposes.
What are the key safety considerations for handling this chemical?
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This is a Danger product, highly flammable (H225), harmful if swallowed (H302), and causes severe skin burns and eye damage (H314), and may cause drowsiness or dizziness (H336). It reacts violently with water and may form explosive peroxides. Strict adherence to safety protocols, including appropriate personal protective equipment (gloves, eye protection, respirator) and working in a well-ventilated area, is essential.
How is this product packed and shipped?
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This chemical is shipped as a UN 2924, Class 8(3), PG I hazardous material, requiring specialised packaging and transport in compliance with international regulations for dangerous goods.
How can I request a sample or quote?
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To request a sample or a quote, please contact our sales team via the website or by phone, providing the product name and CAS number.
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