2-Morpholinoethyl isocyanide
2-Morpholinoethyl isocyanide (CAS: 78375-48-1), a chemical intermediate with the formula C7H12N2O and a molecular weight of 140.18 g/mol, is a versatile building block. Its isocyanide functionality and morpholine ring make it valuable in organic synthesis, particularly for the construction of heterocyclic compounds. This compound is supplied by Tech Serve Solutions for research and development purposes.
- IUPAC
- 4-(2-Isocyanoethyl)morpholine,MEI
- Synonyms
- 4-(2-Isocyanoethyl)morpholine,MEI

Organic Synthesis Intermediate
Utilised as a key building block in the synthesis of complex organic molecules. Its unique isocyanide group allows for diverse reactions like the Passerini and Ugi multi-component reactions.
Heterocyclic Compound Synthesis
A valuable precursor for creating various heterocyclic structures. The morpholine moiety contributes to the structural diversity of the final products, important in medicinal chemistry research.
Reagent in Multi-component Reactions
Serves as a versatile reagent in named reactions such as the Ugi and Passerini reactions, enabling the rapid assembly of complex molecular scaffolds.
| Molecular weight | 140.18 |
|---|---|
| Empirical formula | C7H12N2O |
| Assay | ≥98.0% (GC) |
| Boiling point | 72-73 °C/0.7 mmHg(lit.) |
| Density | 1.017 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.469 |
| Storage temperature | −20°C |

Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H331Toxic if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25-36/37/38 |
| Safety statements (S) | 26-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Morpholinoethyl isocyanide used for?
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2-Morpholinoethyl isocyanide is primarily used as a building block in organic synthesis and for the construction of heterocyclic compounds. It is particularly useful in multi-component reactions like the Ugi and Passerini reactions.
What is the CAS number and formula for 2-Morpholinoethyl isocyanide?
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The CAS number is 78375-48-1 and the empirical formula is C7H12N2O.
What grade and purity does Tech Serve Solutions supply for 2-Morpholinoethyl isocyanide?
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Tech Serve Solutions supplies 2-Morpholinoethyl isocyanide with a purity of ≥98.0% (GC). This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should 2-Morpholinoethyl isocyanide be handled safely?
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2-Morpholinoethyl isocyanide is classified as Danger. It is harmful if swallowed, in contact with skin, and if inhaled, causes skin irritation, and serious eye irritation. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection, must be used. Handle in a well-ventilated area and consult the Safety Data Sheet (SDS) for full handling precautions.
Is 2-Morpholinoethyl isocyanide a controlled substance?
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The provided data does not indicate that 2-Morpholinoethyl isocyanide is a controlled substance.
How is 2-Morpholinoethyl isocyanide packed and exported?
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Tech Serve Solutions adheres to all relevant regulations for the packing and export of chemicals, including hazardous materials like 2-Morpholinoethyl isocyanide (UN 2810 6.1 / PGIII).
How can I request a sample or quote for 2-Morpholinoethyl isocyanide?
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To request a sample or a quote for 2-Morpholinoethyl isocyanide, please contact the Tech Serve Solutions sales team through our website or by phone.
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