2-Methyltetrahydrofuran
2-Methyltetrahydrofuran (CAS 96-47-9, C5H10O) is an anhydrous cyclic ether and a recognised greener alternative solvent. With a molecular weight of 86.13 g/mol, it serves as a versatile building block and reaction medium in chemical synthesis. Its favourable properties make it suitable for various applications, including Grignard reactions, organometallic chemistry, and as a replacement for tetrahydrofuran (THF) in certain processes. TSS supplies this compound in high purity for laboratory and industrial use.
- IUPAC
- 2-MeTHF,Tetrahydro-2-methylfuran,Tetrahydrosilvan
- Synonyms
- 2-MeTHFTetrahydro-2-methylfuranTetrahydrosilvan

Solvent for Organic Synthesis
2-Methyltetrahydrofuran is an effective solvent for a range of organic reactions, including Grignard reagent formation and organometallic chemistry. Its lower miscibility with water compared to THF can be advantageous in certain reaction work-ups.
Greener Solvent Alternative
Recognised as a sustainable and safer solvent alternative, 2-Methyltetrahydrofuran offers a reduced environmental impact and improved safety profile compared to traditional solvents like THF. It is suitable for processes seeking greener chemistry principles.
Building Block in Heterocyclic Chemistry
As a furan derivative, 2-Methyltetrahydrofuran can function as a heterocyclic building block in the synthesis of more complex organic molecules. Its structure allows for diverse chemical modifications.
| Molecular weight | 86.13 |
|---|---|
| Empirical formula | C5H10O |
| Assay | ≥99% |
| Grade | anhydrous |
| Boiling point | 78-80 °C(lit.) |
| Density | 0.86 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.406(lit.) |
| Impurities tested | ≤0.002% water≤0.005% water(100 mL pkg) |

Hazard statements
- H225Highly flammable liquid and vapour
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -12 °C / 10.4 °F |
| Transport (UN / ADR) | UN 2536 3 / PGII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | F |
| Risk statements (R) | 11-19 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Greener Alternative Product Characteristics | Safer Solvents and Auxiliaries |
|---|---|
| Evapn Residue | ≤0.0003% |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methyltetrahydrofuran used for?
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2-Methyltetrahydrofuran is primarily used as a versatile solvent in organic synthesis, particularly for Grignard reactions and organometallic chemistry, and as a greener alternative to THF. It also serves as a building block in heterocyclic chemistry.
What is the CAS number and formula for 2-Methyltetrahydrofuran?
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The CAS number for 2-Methyltetrahydrofuran is 96-47-9, and its molecular formula is C5H10O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Methyltetrahydrofuran with an assay of ≥99% and in anhydrous grade. TSS does not represent this product as USP, BP, or EP grade unless explicitly stated.
How should 2-Methyltetrahydrofuran be handled safely?
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2-Methyltetrahydrofuran is highly flammable (flash point -12 °C) and may form explosive peroxides upon storage. Handle in a well-ventilated area, away from ignition sources, and use appropriate personal protective equipment, including eyeshields, gloves, and a respirator suitable for organic vapours and acid gases.
Is 2-Methyltetrahydrofuran available in Sure/Seal bottles?
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Yes, 2-Methyltetrahydrofuran is available in Sure/Seal bottles, facilitating safe and convenient handling and dispensing of the anhydrous solvent.
How is 2-Methyltetrahydrofuran exported by TSS?
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2-Methyltetrahydrofuran is exported by TSS according to UN 2536, Class 3, Packing Group II regulations, signifying its classification as a flammable liquid.
How can I request a quote or sample for 2-Methyltetrahydrofuran?
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To request a quote or sample of 2-Methyltetrahydrofuran, please contact the Tech Serve Solutions sales team through our website or by phone.
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