2-Methylbenzamide
2-Methylbenzamide (CAS 527-85-5), also known as o-Toluamide, is an organic compound with the linear formula CH3C6H4CONH2 and a molecular weight of 135.16 g/mol. As a valuable building block and carbonyl compound, it plays a role in chemical synthesis. TSS supplies this chemical with an assay of 98%, making it suitable for research and development applications.
- IUPAC
- o-Toluamide
- Synonyms
- o-Toluamide

Organic Synthesis Intermediate
2-Methylbenzamide serves as a key intermediate in the synthesis of more complex organic molecules. Its structure makes it useful for introducing the o-toluoyl moiety in various chemical reactions.
Research and Development
This compound is utilised in laboratory settings for research purposes, including the exploration of new synthetic pathways and the development of novel chemical entities. Its availability as a building block supports diverse research projects.
Total Synthesis Applications
Historically, 2-Methylbenzamide has been employed in the total synthesis of natural products, such as the phenolic protoberberine alkaloid cerasonine, highlighting its utility in complex multi-step syntheses.
| Molecular weight | 135.16 |
|---|---|
| Linear formula | CH3C6H4CONH2 |
| Assay | 98% |
| Solubility | alcohol: very soluble(lit.)benzene: very slightly soluble(lit.)cold water: insoluble(lit.)hydrochloric acid: very soluble (conc.)(lit.)water: very soluble (hot)(lit.) |
| Application | 2-Methylbenzamide (o-Toluamide) has been used in total synthesis of phenolic protoberberine alkaloid, cerasonine1. |
| Melting point | 141-142 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methylbenzamide used for?
+
2-Methylbenzamide is primarily used as an intermediate and building block in organic synthesis and research and development, including in the total synthesis of certain alkaloids.
What is the CAS number and formula for 2-Methylbenzamide?
+
The CAS number for 2-Methylbenzamide is 527-85-5, and its linear formula is CH3C6H4CONH2.
What grade and purity does Tech Serve Solutions supply for 2-Methylbenzamide?
+
Tech Serve Solutions supplies 2-Methylbenzamide with a minimum purity of 98%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 2-Methylbenzamide be handled safely?
+
2-Methylbenzamide is classified as harmful if swallowed (H302). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used during handling to minimise exposure.
Is 2-Methylbenzamide a controlled substance?
+
Based on the provided data, 2-Methylbenzamide is not listed as a controlled substance.
How is 2-Methylbenzamide packed, shipped, and exported?
+
Tech Serve Solutions securely packs and exports 2-Methylbenzamide in compliance with international shipping regulations for chemicals. Specific packaging details are available upon request.
How can I request a quote or sample of 2-Methylbenzamide?
+
To request a quote or sample of 2-Methylbenzamide, please contact our sales team through the TSS website or provide your details via the product inquiry form.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis