2-Methyl-5-(trifluoromethyl)pyrazine
2-Methyl-5-(trifluoromethyl)pyrazine (CAS: 1186195-51-6, Formula: C6H5F3N2, MW: 162.11) is a fluorinated heterocyclic building block. This compound serves as a valuable intermediate in organic synthesis, particularly in the development of novel pharmaceuticals and agrochemicals where the trifluoromethyl group imparts unique electronic and lipophilic properties. Its pyrazine core offers diverse functionalisation possibilities for advanced chemical research and development.

Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs), leveraging the pyrazine scaffold and trifluoromethyl moiety for targeted therapeutic development.
Agrochemical Synthesis
A key building block for the creation of new pesticides and herbicides, where the trifluoromethyl group can enhance efficacy and metabolic stability.
Organic Synthesis Reagent
Employed as a versatile reagent in complex organic transformations, offering a functionalised pyrazine ring for creating diverse molecular structures.
Material Science
Potentially incorporated into advanced materials where its specific electronic and physical properties can be exploited.
| Molecular weight | 162.11 |
|---|---|
| Empirical formula | C6H5F3N2 |
| Assay | 96% |
| Melting point | 38-43 °C |


Hazard statements
- H301Toxic if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Flash point | 48 °C / 118.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-41 |
| Safety statements (S) | 26-39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methyl-5-(trifluoromethyl)pyrazine used for?
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2-Methyl-5-(trifluoromethyl)pyrazine is primarily used as a building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. It is also employed as a reagent in various chemical synthesis pathways.
What are the CAS number and formula for 2-Methyl-5-(trifluoromethyl)pyrazine?
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The CAS number for 2-Methyl-5-(trifluoromethyl)pyrazine is 1186195-51-6, and its molecular formula is C6H5F3N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Methyl-5-(trifluoromethyl)pyrazine with a minimum purity of 96%. This is a technical grade, and we do not represent it as USP, BP, EP, or any other pharmacopoeia standard.
How should 2-Methyl-5-(trifluoromethyl)pyrazine be handled?
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2-Methyl-5-(trifluoromethyl)pyrazine is classified as Danger with hazards H301 (Toxic if swallowed) and H318 (Causes serious eye damage). Handle with extreme care, wearing appropriate personal protective equipment (gloves, eye protection, protective clothing), and avoid ingestion and contact with eyes. Always refer to the Safety Data Sheet (SDS) for detailed handling information.
How is 2-Methyl-5-(trifluoromethyl)pyrazine packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports 2-Methyl-5-(trifluoromethyl)pyrazine in compliance with all relevant transportation regulations for hazardous materials. Packaging is designed to ensure product integrity and safety during transit. We are experienced in global export procedures.
How can I request a quote or sample?
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To request a quote or a sample of 2-Methyl-5-(trifluoromethyl)pyrazine, please contact our sales team via the website or by phone, providing your contact details and the quantity required.
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