2-Methyl-4-nitroaniline
2-Methyl-4-nitroaniline (CAS: 99-52-5), with the molecular formula CH3C6H3(NO2)NH2 and a molecular weight of 152.15 g/mol, is an aromatic amine. This compound serves as a valuable building block in organic synthesis. Its applications span the development of advanced materials, including non-linear optical (NLO) materials and organic electronics, and it is utilised in specialised chemical synthesis processes.
- IUPAC
- 2-Amino-5-nitrotoluene,4-Nitro-o-toluidine

Preparation of Nanofibers
2-Methyl-4-nitroaniline has been employed as a starting material in the electrospinning technique for the fabrication of in-plane aligned nanofibers, contributing to advanced material science.
Synthesis of Chemical Intermediates
It serves as a key reagent in the synthesis of other important chemical compounds, such as 3-chloro-5-methylphenyl isocyanate, facilitating complex organic transformations.
Thin Film Deposition
The compound has been utilised in the deposition of polycrystalline thin films on various substrates including silver, copper, and silicon, employing both conventional and partially ionized beam deposition methods.
| Molecular weight | 152.15 |
|---|---|
| Linear formula | CH3C6H3(NO2)NH2 |
| Assay | 97% |
| Application | 2-Methyl-4-nitroaniline was used in preparing in-plane aligned nanofibers by the electrospinning technique1. It was the starting reagent in the synthesis of 3-chloro-5-methylphenyl isocyanate2. It was used to deposit polycrystalline thin films on Ag, Cu and Si by conventional and partially ionized beam deposition3. |
| Melting point | 130-132 °C(lit.) |



Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H331Toxic if inhaled
- H373May cause damage to organs through prolonged exposure
- H411Toxic to aquatic life with long-lasting effects
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P311Call a POISON CENTER or doctor
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2660 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 23/24/25-33-51/53 |
| Safety statements (S) | 28-36/37-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methyl-4-nitroaniline used for?
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2-Methyl-4-nitroaniline is used in the preparation of nanofibers via electrospinning, as a starting reagent in the synthesis of chemical intermediates like 3-chloro-5-methylphenyl isocyanate, and for depositing thin films on various substrates.
What is the CAS number and formula for 2-Methyl-4-nitroaniline?
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The CAS number is 99-52-5 and the molecular formula is CH3C6H3(NO2)NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Methyl-4-nitroaniline with an assay of 97%. This product is not supplied as USP, BP, EP, or any other pharmacopoeia grade and is intended for research and chemical synthesis purposes.
How should 2-Methyl-4-nitroaniline be handled safely?
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2-Methyl-4-nitroaniline is classified as Dangerous. It is toxic if swallowed, in contact with skin, or if inhaled, and may cause damage to organs through prolonged or repeated exposure. It is also toxic to aquatic life with long lasting effects. Appropriate personal protective equipment, including a dust mask (N95), eyeshields, faceshields, gloves, and a P2 respirator cartridge, should be used. Handle in a well-ventilated area.
How is 2-Methyl-4-nitroaniline packed and shipped?
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2-Methyl-4-nitroaniline is shipped as a UN 2660, Hazard Class 6.1, Packing Group III substance. Packaging adheres to strict international regulations for hazardous materials.
How can I request a quote or sample for 2-Methyl-4-nitroaniline?
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To request a quote or a sample of 2-Methyl-4-nitroaniline, please contact our sales department through the website or by phone.
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