2-Methoxyphenyl chloroformate
2-Methoxyphenyl chloroformate (CAS: 2293-75-6) is a chemical intermediate with the linear formula ClCO<sub>2</sub>C<sub>6</sub>H<sub>4</sub>OCH<sub>3</sub> and a molecular weight of 186.59 g/mol. This reactive compound belongs to the acid halide class and serves as a versatile building block in organic synthesis. It is primarily utilised in chemical research and development for the introduction of the 2-methoxyphenylcarbonyl group into various molecules.

Organic Synthesis Reagent
2-Methoxyphenyl chloroformate acts as a key reagent in the formation of esters and carbonates. Its reactivity allows for efficient acylation reactions in the synthesis of complex organic molecules.
Pharmaceutical Intermediate
This compound can be employed in the multi-step synthesis pathways for active pharmaceutical ingredients. It facilitates the introduction of specific structural motifs required for biological activity.
Research and Development
Utilised in academic and industrial laboratories for exploring novel chemical transformations and developing new synthetic methodologies. It is a valuable tool for chemists investigating new reaction pathways.
| Molecular weight | 186.59 |
|---|---|
| Linear formula | ClCO2C6H4OCH3 |
| Assay | 98% |
| Boiling point | 244 °C(lit.) |
| Density | 1.253 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.519(lit.) |


Hazard statements
- H301Toxic if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 3277 6.1/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,C |
| Risk statements (R) | 25-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methoxyphenyl chloroformate used for?
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2-Methoxyphenyl chloroformate is used as a reagent in organic synthesis, primarily for introducing the 2-methoxyphenylcarbonyl group, and as an intermediate in the synthesis of complex organic molecules and potential pharmaceutical agents.
What is the CAS number and formula for 2-Methoxyphenyl chloroformate?
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The CAS number is 2293-75-6 and the linear formula is ClCO₂C₆H₄OCH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Methoxyphenyl chloroformate with a minimum assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Methoxyphenyl chloroformate be handled?
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2-Methoxyphenyl chloroformate is a dangerous substance, classified with Danger signal word, H301 (Toxic if swallowed) and H314 (Causes severe skin burns and eye damage). It requires strict adherence to safety protocols, including wearing appropriate personal protective equipment such as gloves, goggles, face shields, and respiratory protection. Handle only in well-ventilated areas or fume hoods.
How is 2-Methoxyphenyl chloroformate packed and shipped?
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2-Methoxyphenyl chloroformate is packed and shipped according to international regulations for hazardous materials, including UN 3277, Class 6.1, Packing Group II. TSS is a specialist global supplier and exporter.
How can I request a sample or quote for 2-Methoxyphenyl chloroformate?
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To request a sample or a quote for 2-Methoxyphenyl chloroformate, please contact our sales department through the website or by phone.
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