2-Methoxybenzoyl chloride
2-Methoxybenzoyl chloride (CAS: 21615-34-9), with the molecular formula C<sub>8</sub>H<sub>7</sub>ClO<sub>2</sub> and a molecular weight of 170.59 g/mol, is a key organic building block. This acid halide is primarily utilised in chemical synthesis, particularly in Friedel-Crafts acylations and the formation of ester and amide derivatives, contributing to the development of complex organic molecules.
- IUPAC
- o-Anisoyl chloride
- Synonyms
- o-Anisoyl chloride
Friedel-Crafts Acylation
2-Methoxybenzoyl chloride serves as an acylating agent in Friedel-Crafts reactions, as demonstrated in its use for the preparation of 2-methoxybenzoyl-ferrocene.
Synthesis of Phosphate Esters
It is employed in reactions leading to the formation of phosphate esters, such as 2-methoxybenzoyl phosphate, relevant in synthetic organic chemistry.
Precursor for Organic Synthesis
As a versatile building block, it facilitates the introduction of the 2-methoxybenzoyl moiety into various organic structures, enabling the synthesis of diverse compounds.
| Molecular weight | 170.59 |
|---|---|
| Linear formula | CH3OC6H4COCl |
| Assay | 97% |
| Boiling point | 128-129 °C/8 mmHg(lit.) |
| Density | 1.146 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.572(lit.) |
| Application | 2-Methoxybenzoyl chloride has been used in preparation of:• 2-methoxybenzoyl-ferrocene Friedel Crafts reaction with ferrocene1• 2-methoxybenzoyl phosphate2 |
Hazard statements
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 84 °C / 183.2 °F |
| Transport (UN / ADR) | UN 1729 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-36/37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methoxybenzoyl chloride used for?
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2-Methoxybenzoyl chloride is used as an acylating agent in organic synthesis, notably in Friedel-Crafts reactions and for preparing compounds like 2-methoxybenzoyl-ferrocene and 2-methoxybenzoyl phosphate.
What is the CAS number and molecular formula for 2-Methoxybenzoyl chloride?
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The CAS number for 2-Methoxybenzoyl chloride is 21615-34-9, and its linear molecular formula is CH3OC6H4COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Methoxybenzoyl chloride with a minimum assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Methoxybenzoyl chloride be handled safely?
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2-Methoxybenzoyl chloride is a corrosive substance that can cause severe skin burns and eye damage, and may cause respiratory irritation (H314, H335). Handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, in a well-ventilated area.
How is 2-Methoxybenzoyl chloride packed and shipped?
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2-Methoxybenzoyl chloride is shipped as a UN 1729, Class 8, Packing Group II hazardous material, according to international shipping regulations.
How can I request a sample or quote for 2-Methoxybenzoyl chloride?
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Please contact our sales team via our website or by phone to request a sample or a formal quotation for 2-Methoxybenzoyl chloride.
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