2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS: 1195-66-0) is an organoborate compound with the molecular formula C7H15BO3 and a molecular weight of 158.00 g/mol. This compound serves as a valuable reagent in organic synthesis, particularly in cross-coupling reactions. Its structure, featuring a boronic acid pinacol ester, makes it a versatile building block for introducing methoxyboronate functionalities into complex molecules.
- IUPAC
- Methoxyboronic acid pinacol ester
- Synonyms
- Methoxyboronic acid pinacol ester2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Suzuki-Miyaura Cross-Coupling Reactions
This organoboronate ester is frequently employed as a coupling partner in Suzuki-Miyaura reactions. It facilitates the formation of carbon-carbon bonds by reacting with organic halides or pseudohalides in the presence of a palladium catalyst.
Organic Synthesis Reagent
As a versatile organoboron compound, it is used in various other synthetic transformations. It acts as a building block for the synthesis of more complex organic molecules, including pharmaceuticals and advanced materials.
Preparation of Boron-Containing Compounds
It is utilised in the synthesis of specialised boron-containing organic compounds. The pinacol ester protection allows for controlled reactivity and stability during synthetic procedures.
| Molecular weight | 158.00 |
|---|---|
| Empirical formula | C7H15BO3 |
| Assay | 96% |
| Density | 0.9642 g/mL at 25 °C |
| Refractive index | n20/D 1.4096 |
Hazard statements
- H226Flammable liquid and vapour
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 42 °C / 107.6 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane used for?
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This compound is primarily used as a reagent in organic synthesis, notably in Suzuki-Miyaura cross-coupling reactions and for the preparation of other boron-containing organic molecules.
What is the CAS number and formula for 2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane?
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The CAS number is 1195-66-0 and the molecular formula is C7H15BO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with a minimum assay of 96%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated in the product specifications.
How should 2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane be handled safely?
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This compound is flammable and can cause serious eye irritation. Handle in a well-ventilated area, away from ignition sources. Wear appropriate personal protective equipment, including safety glasses, gloves, and a suitable respirator, and follow P305 + P351 + P338 precautionary statements.
Is 2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane a controlled substance?
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The provided data does not indicate that 2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a controlled substance.
How is 2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane shipped and exported?
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This chemical is shipped and exported according to international regulations for hazardous materials. It is classified under UN 1993, Hazard Class 3, Packing Group III.
How can I request a quote or sample?
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Please contact our sales team via the website or by phone to request a quote or a sample of 2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane.
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