2′-Hydroxyacetophenone
2′-Hydroxyacetophenone (CAS 118-93-4) is an organic compound with the linear formula HOC<sub>6</sub>H<sub>4</sub>COCH<sub>3</sub> and a molecular weight of 136.15 g/mol. This ortho-substituted acetophenone derivative is a valuable building block in organic synthesis. It is frequently employed in the production of pharmaceuticals, agrochemicals, and speciality chemicals due to its reactive functional groups.
- IUPAC
- 2-Acetylphenol
- Synonyms
- 2-Acetylphenolo-Hydroxyacetophenone1-(2-Hydroxyphenyl)ethanoneortho-Acetylphenol
Pharmaceutical Intermediate
2′-Hydroxyacetophenone serves as a key intermediate in the synthesis of various pharmaceutical compounds. Its structure allows for further derivatization to create complex active pharmaceutical ingredients (APIs).
Organic Synthesis Reagent
As a versatile building block, it is utilised in a wide range of organic transformations. Its phenolic hydroxyl and ketone functionalities enable diverse reaction pathways for creating novel molecules.
Agrochemical Production
The compound finds application in the development and manufacturing of agrochemicals. It can be incorporated into molecular structures designed for crop protection and enhancement.
Speciality Chemical Manufacturing
2′-Hydroxyacetophenone is employed in the synthesis of various speciality chemicals, contributing to the creation of materials with specific properties for niche applications.
| Molecular weight | 136.15 |
|---|---|
| Linear formula | HOC6H4COCH3 |
| Assay | 98% |
| Grade | ReagentPlus® |
| Boiling point | 213 °C/717 mmHg(lit.) |
| Density | 1.133 g/mL at 20 °C1.131 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.558(lit.) |
| Melting point | 3-6 °C(lit.) |
| Vapour pressure | ~0.2 mmHg (20 °C) |
| Vapour density | 4.7 (vs air) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 106 °C / 222.8 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′-Hydroxyacetophenone used for?
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2′-Hydroxyacetophenone is primarily used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and speciality chemicals. It is also a versatile building block in general organic synthesis.
What is the CAS number and chemical formula for 2′-Hydroxyacetophenone?
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The CAS number for 2′-Hydroxyacetophenone is 118-93-4. Its linear formula is HOC<sub>6</sub>H<sub>4</sub>COCH<sub>3</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2′-Hydroxyacetophenone in ReagentPlus® grade with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 2′-Hydroxyacetophenone be handled safely?
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2′-Hydroxyacetophenone is classified with hazards including skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Always handle with appropriate personal protective equipment, including eyeshields and gloves, and ensure adequate ventilation. Consult the Safety Data Sheet for full details.
How is 2′-Hydroxyacetophenone packed, shipped, and exported?
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Tech Serve Solutions offers robust packaging suitable for global export, adhering to international shipping regulations for chemicals. Please contact us for specific shipping and export inquiries.
How can I request a sample or quote for 2′-Hydroxyacetophenone?
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To request a sample or a quote for 2′-Hydroxyacetophenone, please use the 'Request a Quote' or 'Request a Sample' button on our product page or contact our sales team directly.
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